Visceral Leishmaniasis in a Child

소아에서 진단된 Visceral Leishmaniasis

  • Kim, Hyun-Young (Department of Surgery, Seoul National University College of Medicine) ;
  • Jung, Seung-Eun (Department of Surgery, Seoul National University College of Medicine) ;
  • Park, Kwi-Won (Department of Surgery, Seoul National University College of Medicine) ;
  • Kim, Woo-Ki (Department of Surgery, Seoul National University College of Medicine)
  • 김현영 (서울대학교 의과대학 외과학교실) ;
  • 정성은 (서울대학교 의과대학 외과학교실) ;
  • 박귀원 (서울대학교 의과대학 외과학교실) ;
  • 김우기 (서울대학교 의과대학 외과학교실)
  • Published : 2004.06.30

Abstract

Visceral leishmaniasis is a life-threatening systemic infection caused by a protozoa of the genus leishmania and transmitted by sandfly. We report the first case of visceral leishmanaisis in Korea. The patient was a one-year-old girl admitted with the symptoms of fever, abdominal distension. pancytopenia, and purpura. She traveled to Argentina 5 months ago, and has had symptoms such as fever and pale appearance. Laboratory findings were: WBC, 12.680/$mm^3$; Hg, 3.7g/dL; platelet, 100K; total bilirubin, 1.2mg/dL; AST/ALT, 48/10 U/L. CT scan and MRI showed hepato-splenomegaly. On laparotomy, excision of an accessory spleen and splenic hilar lymph nodes were performed. Many amastigotes were microscopically identified in histiocytes from the biopsy tissues. Sodium stibogluconate was administrated for 2 weeks, which did not relieve the symptoms. After administration of the additional Amphotericin B for 3 weeks, symptoms were improved.

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