Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effect of Kamichungbieum on Immune Reaction

가미청비음이 면역반응에 미치는 영향

  • 은재순 (우석대학교 약학대학) ;
  • 이동희 (우석대학교 약학대학) ;
  • 전용근 (우석대학교 약학대학) ;
  • 권영안 (우석대학교 자연과학대학) ;
  • 권진 (군장대학 의무행정과)
  • Published : 2004.10.01
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Abstract

The purpose of this research was to investigate the effects of supercritical fluid extract of Kamichungbieum (SFE) on immune reaction. SFE did not affect the subpopulation of murine splenocytes and increased the production of interleukin-2 in serum. Also, SFE inhibited the influx of Ca/sup 2+/ into mast cells and the release of histamine from mast cells. Furthermore, SFE decreased the phagocytic activity of murine macrophages, These results indicate that SFE may be useful for the treatment of allergy related disease via inhibition of histamine release from mast cells and decrease of phagocytic activity of murine macrophages.

Keywords

References

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