Korean Journal of Materials Research (한국재료학회지)

Materials Research Society of Korea (한국재료학회)
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Effect of HA Crystals Precipitated by Hydrothermal-Treatment on the Bioactivity of Ti-6Al-7Nb Alloy

열수처리에 의해 석출된 HA 결정이 Ti-6Al-7Nb 합금의 생체활성에 미치는 영향

  • Kwon O. S. (School of Advanced Materials Engineering, Chonbuk National University & Biomaterials Institute, 2M, Co., Chonbuk National University) ;
  • Choi S. K. (Megagen Corp.) ;
  • Moon J. W. (Dept. of Dental Materials, Dept. of Conservative Dentistry & Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Lee M. H. (Dept. of Dental Materials, Dept. of Conservative Dentistry & Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Bae T. S. (Dept. of Dental Materials, Dept. of Conservative Dentistry & Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Lee O. Y. (School of Advanced Materials Engineering, Chonbuk National University & Biomaterials Institute, 2M, Co., Chonbuk National University)
  • 권오성 (전북대학교 공과대학 신소재공학부, 투엠생체재료연구소) ;
  • 최석규 ((주) 메가젠) ;
  • 문장원 (전북대학교 치과대학 치과생체재료학교실, 치과보존학교실 및 구강생체과학연구소) ;
  • 이민호 (전북대학교 치과대학 치과생체재료학교실, 치과보존학교실 및 구강생체과학연구소) ;
  • 배태성 (전북대학교 치과대학 치과생체재료학교실, 치과보존학교실 및 구강생체과학연구소) ;
  • 이오연 (전북대학교 공과대학 신소재공학부, 투엠생체재료연구소)
  • Published : 2004.09.01
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Abstract

This study was to investigate the surface properties of electrochemically oxidized Ti-6Al-7Nb alloy by anodic spark discharge technique. Anodizing was performed at current density 30 $mA/cm^2$ up to 300 V in electrolyte solutions containing $DL-{\alpha}$-glycerophosphate disodium salt hydrate($DL-{\alpha}$-GP) and calcium acetate (CA). Hydrothermal treatment was done at $300^{\circ}C$ for 2 hrs to produce a thin outermost layer of hydroxyapatite (HA). The bioactivity was evaluated from HA formation on the surfaces in a Hanks' solution with pH 7.4 at $36.5^{\circ}C$ for 30 days. The size of micropores and the thickness of oxide film increased and complicated multilayer by increasing the spark forming voltage. Needle-like HA crystals were observed on anodic oxide film after the hydrothermal treatment at $300^{\circ}C$ for 2 hrs. When increasing $DL-{\alpha}$-GP in electrolyte composition, the precipitated HA crystals showed the shape of thick and shorter rod. However, when increasing CA, the more fine needle shape HA crystals were appeared. The bioactivity in Hanks' solution was accelerated when the oxide films composed with strong anatase peak with presence of rutile peak. The increase of amount of Ca and P was observed in groups having bioactivity in Hanks' solution. The Ca/P ratio of the precipitated HA layer was equivalent to that of HA crystal and it was closer to 1.67 as increasing the immersion time in Hanks' solution.

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References

  1. H. W. Chung, D. H. Won, T. S. Bae and M. H. Lee, J. Korean Res. Soc. Dent. Mater., 28, 223 (2001)
  2. K. Hayashi, T. Inadome, T. Mashima and Y Sugioka, J. Biomed. Mater. Res., 27, 557 (1993) https://doi.org/10.1002/jbm.820270502
  3. M. H. Lee, D. J. Yoon, D. H. Won, T. S. Bae and F. Watari, Metals and Materials Int., 8, 35 (2003)
  4. T. Hanawa, K. Asami and K. Asaoka, Corros. Sci., 38, 1579 (1996) https://doi.org/10.1016/0010-938X(96)00053-4
  5. K, H. Cho, M. Y. Kim, K. Y. Song, T. S. Bae and M. H. Lee, J. Korean Res. Soc. Dent. Mater., 29, 263 (2002)
  6. D. Buser, R. K. Schenk, S. Steinemann, J. P. Fiorellini, C. H. Fox and H. Stich, J. Biomed. Mater. Res., 25, 889 (1991) https://doi.org/10.1002/jbm.820250708
  7. C. Larsson, P. Thomsen, B. O. Aronssen and et al., Biomaterials, 17, 605 (1996) https://doi.org/10.1016/0142-9612(96)88711-4
  8. B. Groessner-Schreiber and R. S. Tuan, J. Cell Sci., 101, 209 (1992)
  9. T. Albrektsson, P-I, Branemark, H. A. Hansson and J. Lindstrom, Acta. Orthop. Scand., 52, 155 (1981) https://doi.org/10.3109/17453678108991776
  10. B. Chehroudi, T. R. L. Gould and D. M. Brunette, J. Biomed. Mater. Res., 23, 1067 (1989) https://doi.org/10.1002/jbm.820230907
  11. H. Ishizawa and M. Ogino, J. Biomed. Mater. Res., 29, 1071 (1995) https://doi.org/10.1002/jbm.820290907
  12. M. Fini, A. Cigada, G. Rondelli, R. Chiesa, R. Giardino, G. Giavaresi, N. N. Aldini, P. Toricelli and B. Vicentini, Biomaterials, 20, 1587 (1999) https://doi.org/10.1016/S0142-9612(99)00060-5
  13. X. Zhu, K. H. Kim and Y. S. Jeong, Biomaterials, 22, 2199 (2001) https://doi.org/10.1016/S0142-9612(00)00394-X
  14. O. R. Camara, C. P. De Pauli and M. C. Giordano, Electrochimica Acta., 29, 1111 (1984) https://doi.org/10.1016/0013-4686(84)87163-7
  15. A. Felske and W. J. Plieth, Electrochimica Acta., 34, 75 (1989) https://doi.org/10.1016/0013-4686(89)80012-X
  16. T. Hirata, T. Nakamura, F. Takashima, T. Maruyama, M. Taira and J. Takahashi, J. Oral Rehab., 28, 773 (2001) https://doi.org/10.1046/j.1365-2842.2001.00737.x
  17. T. Kawazoe and K. Suese, J. Dent. Med., 30, 317 (1989)
  18. A. Kuroiwa and Y. Igarashi, J. Jpn. Prosthodont Soc., 42, 547 (1998) https://doi.org/10.2186/jjps.42.547
  19. R. C. Browne, Br. J. Ind. Med., 12, 57 (1955)
  20. S. G. Sjoberg, Acta. Med. Scand., 154, 381 (1956) https://doi.org/10.1111/j.0954-6820.1956.tb14333.x
  21. P. G. Laing, ASTM-STP, 684, 199 (1979)
  22. Z. Cai, T. Shafer, I. Watanabe, M. E. Nunn and T. Okabe, Biomaterials, 24, 213 (2003) https://doi.org/10.1016/S0142-9612(02)00293-4
  23. D. Iijima, T. Toneyama, H. Doi, H. Hamanaka and N. Kurosaki, Biomaterials, 24, 1519 (2003) https://doi.org/10.1016/S0142-9612(02)00533-1
  24. K. Wang, Mater. sci. Eng., A213, 134 (1996) https://doi.org/10.1016/0921-5093(96)10243-4
  25. M. Long and H. J. Rack, Biomaterials, 19, 1621 (1998) https://doi.org/10.1016/S0142-9612(97)00146-4
  26. P. J. Li, C. Ohtsuki, T. Kokubo, K. Nakanishi, N. Soga and K. de Groot, J. Biomed. Mater. Res., 28, 7 (1994) https://doi.org/10.1002/jbm.820280103
  27. B. C. Yang, J. Weng, X. D. Li and X. D. Zhang, J. Biomed. Mater. Res., 47, 213 (1999) https://doi.org/10.1002/(SICI)1097-4636(199911)47:2<213::AID-JBM11>3.0.CO;2-C
  28. H. Takadama, H. M. Kim, T. Kokubo and T. Nakamura, J. Biomed. Mater. Res., 55, 185 (2001) https://doi.org/10.1002/1097-4636(200105)55:2<185::AID-JBM1005>3.0.CO;2-P
  29. M. C. Bryan, Nature, 260, 727 (1976) https://doi.org/10.1038/260727a0