Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

Effects of Aqua-Acupuncture of Jibaikjihwangtang on the Blood Pressure in Hypertensive Rats

지백지황탕(知柏地黃湯) 약침(藥鍼)이 혈압(血壓)에 미치는 영향(影響)

  • Shim, Yang-soo (Department of Acupoint, College of Oriental Medicine, Wonkwang University) ;
  • Jeon, Moon-ki (Department of Acupoint, College of Oriental Medicine, Wonkwang University) ;
  • Kim, Kyung-sik (Department of Acupoint, College of Oriental Medicine, Wonkwang University) ;
  • Sohn, In-chul (Department of Acupoint, College of Oriental Medicine, Wonkwang University)
  • 심양수 (원광대학교 한의과대학 경혈학교실) ;
  • 전문기 (원광대학교 한의과대학 경혈학교실) ;
  • 김경식 (원광대학교 한의과대학 경혈학교실) ;
  • 손인철 (원광대학교 한의과대학 경혈학교실)
  • Received : 2004.06.08
  • Accepted : 2004.07.25
  • Published : 2004.08.20
Download PDF
⟨ Previous Next ⟩

Abstract

Objective : This study was performed to investigate the effects of aqua-acupuncture of Jibaikjihwangtang in two-kidney one clip Goldblatt hypertensive rats and spontaneously hypertensive rats. Methods : we injected aqua-acupuncture solution into Shin-Soo ($BL_{23}$) which corresponds to human acupuncture point in two-kidney one clip Goldblatt hypertensive rats and spontaneously hypertensive rats. Systolic blood pressure, renin activity, aldosterone and atrial natriuretic peptide (ANP) plasma levels were tested. Results : Systolic blood pressure decreased significantly after aqua-acupuncture of jibaikjihwangtang. Acupuncture group in two-kidney one clip Goldblatt hyper-tensive rats had deference with control group. In plasma levels of atrial natriuretic peptide, acupuncture group of spontaneously hypertensive rats increased meaningfully but to two-kidney one clip Goldblatt hypertensive rats it was decreased meaningfully. In Serum Aldosterone density, the acupuncture group of spontaneously hypertensive rats had significant alteration than control group, but the acupuncture group of two-kidney one clip Goldblatt hypertensive rats had decreased alteration than control group. Conclusion : According to these results, after Aqua-Acupuncture of Jibaikjihwangtang blood pressure decreased significantly and data suggest that blood pressure reduction activity connected with renin activity reduction in renal hypertensive rat.

Keywords