Magnetic Resonance Imaging in Thorax

흉부의 자기공명영상

  • Choi, Byoung Wook (Department of Diagnostic Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine)
  • 최병욱 (연세대학교 의과대학 영상의학과)
  • Published : 20040000

Abstract

Magnetic Resonance Imaging (MRI) is one of the most advanced imaging techniques in clinical and research medicine. However, clinical application of MRI to the lung or thorax has been limited due to various drawbacks. Low signal intensity of the lung and cardiac and respiratory movements are the most serious problems with MRI in thorax. Nevertheless, MRI is superior to CT in some selected patients with thoracic diseases. The role of clinical MRI in thoracic disease has been widened with improvement of MR equipments and development of new pulse sequences. Otherwise, functional assessment of lung by MRI has been studied for the last decade. These include perfusion MRI with or without contrast enhancement and ventilation MRI with oxygen-enhancement or hyperpolarized noble gas, $^3He$ and $^{129}Xe$.

Keywords

References

  1. Bergin CJ, Glover GH, Pauly JM, Lung parenchyma: magnetic susceptibility in MR imaging. Radiology 1991; 2:1236-9
  2. Cuttillo AG, Ganesan K, Ailion DC, Morris AH, Durney CH, Symko SC, et al. Alveolar air-tissue interface and nuclear magnetic resonance behavior of lung. J Appl Physiol 1991; 70:2145-54
  3. Albert MS, Cates GD, Driehuys B, Driehuys B, Happer W, Saam B, et al. Biological magnetic resonance imaging using laserpolarized 129Xe. Nature 1994; 370:199-201
  4. Wang SC, Fischer KC, Slone RM, Gierada DS, Yusen RD, Lefrak SS, et al. Perfusion scintigraphy in the evaluation for lung volume reduction surgery: correlation with clinical outcome. Radiology 1997; 205:243-8
  5. Ruppert K, Brookeman JR, Hagspiel KD, Mugler JP 3rd. Probing lung physiology with xenon polarization transfer contrast (XTC). Magn Reson Med 2000; 44:349-57
  6. Chen XJ, Chawla MS, Hedlund LW, Moller HE, MacFall JR, Johnson GA. MR micro scopy of lung airways with hyperpolarized $^3He$. Magn Reson Med 1998; 39:79-84
  7. Viallon M, Cofer GP, Suddarth SA, Moller HE, Chen XJ, Chawla MS, et al. Functional MR microscopy of the lung using hyper polarized $^3He$. Magn Reson Med 1999;41:787-92
  8. Saam BT, Yablonskiy DA, Kodibagkar VD, Leawoods JC, Gierada DS, Cooper JD, et al. MR imaging of diffusion of $^3He$ gas in healthy and diseased lungs. Magn Reson Med 2000; 44:174-9
  9. Alters TA, Powers PL, Knight-Scott J, Pakes G, Platts-Mills TA, de Lange EE, et al. Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings. J Magn Reson Imaging 2001; 13:378-84
  10. Salemo M, de Lange EE, Altes TA, Truwit JD, Brookeman JR, Mugler JP $3^{rd}$, et al. Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes-initial experience. Radiology 2002; 222:252-60
  11. Edelman RR, Hatabu H, Tadamura E, Li W, Prasad PV. Noninvasive assessment of regional ventilation in the human lung using oxygen-enhanced magnetic resonance imaging. Nat Med 1996; 2:1236-9
  12. Young IR, Clarke GH, Bailes DR, Pennock JM, Doyle FH, Bydder GM. Enhancement of relaxation rate with paramagnetic contrast agents in NMR imaging. J Comput Tomogr 1981; 5:543-6
  13. Tadamura E, Hatabu H, Li W, Prasad PV, Edelman RR. Effect of oxygen inhalation on relaxation times in various tissues. J Magn Reson Imaging 1997; 7:220-5
  14. Loffler R, Muller CJ, Peller M, Penzkofer H, Deimling M, Schwaiblmair M, et al. Optimization and evaluation of the signal intensity change in multiscetion oxygen-enhanced MR lung imaging. Magn Reson Med 2000;43:860-6
  15. Ohno Y, Hatabu H, Takenaka D, Adachi S, Van Cauteren M, Sugimura K. Oxygenenhanced MR ventilation imagingof the lung: preliminary clinical experience in 25 subjects AJR Am J Roentgenol 2001; 177:185-94
  16. Ohno Y, Hatabu H, Takenaka D, Van Cau teren M, Fujii M, Sugimura K. Dynamic oxygen-enhanced MRI reflects diffusing capa city of the lung. Magn Reson Med 2002;47:1139-44
  17. Ohno Y, Chen Q, Hatabu H. Oxygen-enhanced magnetic resonance ventilation imaging of lung. Eur J Radiol 2001; 37:164-71
  18. Muller CJ, Schwaiblmair M, Scheidler J, Deimling M, Weber J, Loffler RB, et al. Pulmonary diffusing capacity assessment with oxygen-enhanced lung MR imaging preliminary findings. Radiology 2002;222:499-506
  19. Nakagawa T, Sakuma H, Murashima S, Ishida N, Matsumura K, Takeda K, et al. Pulmonary ventilation-perfusion MR imaging in clinical patients. J Magn Reson Imaging 2001; 14:419-24
  20. Hatabu H, Gaa J, Kim D, Li W, Prasad PV, Edelman RR, et al. Pulmonary perfusion: qualitative assessment with dynamic contrast-enhanced MRI using ultra-short TE and inversion recovery turbo FLASH. Magn Reson Med 1996; 36:503-8
  21. Berthezene Y, Croisille P, Wiart M, Howarth N, Houzard C, Faure O, et al. Prospective comparison of MR lung perfusion and lung scintigraphy. J Magn Reson Imaging 1999;9:61-8
  22. Lvein DL, Chen Q, Zhang M, Edelman RR, Hatabu H. Evaluation of regional pulmonary perfusion using ultrafast magnetic resonance imaging. Magn Reson Med 2001; 46:166-71
  23. Edelman RR, Siewert B, Adamis M, Gaa J, Laub G, Wielopolski P. Signal targeting with alternating radiofrequency (STAR) sequences: application to MR angiography. Magn Reson Med 1994; 31:233-38
  24. Mai VM, Hagspiel KD, Christopher JM, Do HM, Altes T, Knight-Scott J, et al. Perfusion imaging of the human lung using flowsensitive alternating inversion recovery with an extra radiofrequency pulse (FAIRER). Magn Reson Imaging 1999; 17:355-61.
  25. Roberts DA, Gefter WB, Hirsch JA, Rizi RR, Dougherty L, Lenkinski RE, et al. Pulmonary perfusion: respiratory-triggered three-dimen sional MR imaging with arterial spin tag ging-preliminary results in healthy volunte ers. Radiology 1999; 212:890-5
  26. Naidich DP, Webb WR, Müller NL, Krinsky GA, Zerhouni EA, Siegelman SS, et al. Computed tomography and magnetic resonance of the thorax. $3^{rd}$ ed. Philadelphia: Lippincott-Raven Publishers; 1999
  27. Hatabu H, Stock KW, Sher S, Edinburgh KJ, Levin DL, Garperstad E, et al. Magnetic resonance imaging of the thorax. Past, present, and future. Radiol Clin North Am 2000; 38:593-620
  28. Hashemi RH, Bradley WG Jr. MRI the basics, $1^{st}$ ed. Baltimore: Williams & Wilkins; 1997
  29. Meaney JF, Prince MR. Pulmonary MR angiography. Magn Reson Imaging Clin N Am 1999; 7:393-409
  30. Rahmouni A, Tempany C, Jones R, Mann R, Yang A, Zerhouni E. Lymphoma: monitoring tumor size and signal intensity with MR imaging. Radiology 1993; 188:445-51