Food Science and Preservation (한국식품저장유통학회지)

The Korean Society of Food Preservation (한국식품저장유통학회)
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Physiological Activity of Medicinal Plant Extracts

생약재 추출물의 생리활성 효과

  • Published : 2004.09.01
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Abstract

The physiological activity of 5 kinds of medicinal plant extracts were examined. Total polyphenol contents showed the highest value in 50 $\%$ ethanol extracts. Electron donating ability showed the highest value in 50 $\%$ ethanol extracts of Glycyrrhiza uralensis. SOD-like activity showed the highest activity in 50$\%$ ethanol extracts of Glycyrrhiza uralensis. Medicinal plant extracts showed the different nitrite scavenging abilities under the different pH conditions. Medicinal plant extracts showed the highest value in nitrite scavenging ability at pH 1.2. The maximum nitrite scavenging effect was found at pH 1.2 and decreased as pH increased. Angiotensin-converting enzyme inhibitory activity showed the highest value in 50 $\%$ ethanol extracts of dried garlic.

생약재의 용매별 추출액에 대한 생리활성 측정 결과 총폴리페놀 함량은 모든 생약재가 50$\%$ ethanol 추출액에서 가장 우수하였으며, 생약재 별로는 감초의 50$\%$ ethanol 추출액이 2.23$\%$로 가장 높은 함량을 나타내었다. 전자공여 작용은 감초 water 추출액이 81.81$\%$로 가장 우수하였으며, 감초, 건강는 water 추출액이 두충, 건마늘, 인삼은 50$\%$ ethanol 추출액에서 다른 용매에 비해 높은 전자공여 효과를 나타내었다. Superoxide dismutase(SOD) 유사활성은 감초의 10$\%$ ethanol추출액이 42.75$\%$로 가장 높은 활성을 나타냈었고, 전마늘, 건강은 50$\%$ ethanol 추출액이 감초, 두충, 인삼은 water 추출액이 다른 용매에 비해 우수한 것으로 나타났다. 아질산염소거작용은 pH가 증가할 수록 소거율이 크게 감소하는 것으로 나타났다. 또한 용매별 소거능은 뚜렷한 차이를 보이지 않았지만 water 추출액이 다른 두 용매 추출액에 비해 소거능이 높은 것으로 나타났다. ACE 저해작용은 건강을 제외한 생약재 추출물에서 50$\%$ ethanol 추출물이 다른 용매에 비해 우수한 효과를 나타내었으며, 건마늘의 50$\%$ ethanol 추출물이 37.16$\%$로 가장 높은 저해 활성을 나타내었다. 용매별 효과는 50$\%$ ethanol 추출액이 다른 용매에 비해 ACE저해활성이 우수한 것으로 나타났다. 따라서 생약재의 종류에 따라 다름을 알 수 있다. 또한 기능성 효과를 확인함으로써 기능성 식품의 소재로의 이용가능성을 확인하였다.

Keywords

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