The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
권호 표지

The Effects of Ultrasound Irradiation on the Heat Shock Protein 70(HSP70) Expression in Rat Knee Articular Cartilage after Immobilization

흰쥐 슬관절 고정 후 초음파 적용이 관절연골내 HSP70의 발현에 미치는 영향

  • Nam, Ki-Won (Lab. of Nerve Regeneration, Department of Physical Therapy, College of Rehabilitation, Daegu University)
  • 남기원 (대구대학교 재활과학대학 물리치료학과 신경재생실)
  • Published : 2005.09.26
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of the study was for investigating the effect of therapeutic ultrasound irradiation on HSP70 expression in knee of degraded rat articular cartilage. Knee of ten Sprague-Dawley male rats were immobilized for 4 weeks and divided at random into the control and continuous ultrasound applicated group. The continuous ultrasound applicated group was irradiated with frequency 1MHz, intensity $1W/cm^2$ for 5 minutes. The control group was sham sonication. The immunoreactivity of HSP70 was increased in degraded articular cartilage after untrasound irradiation. These results suggest that therapeutic ultrasound can enhance HSP70 expression in degraded articular cartilage.

Keywords