The Effects of Reinforcing Acupoint of Heart JEONGGYEOK, Reinforcing Acupoint of Kidney JEONGGYEOK, Combination of Reinforcing Acupoint of Heart JEONGGYEOK and Kidney JEONGGYEOK, Reinforcing and Reducing Acupoint of Heart JEONGGYEOK on Focal Ischemia Induced by Inserted Intraluminal Filament in MCA of Rats

심정격(心正格)의 보혈(補穴), 신정격(腎正格)의 보혈(補穴), 심정격(心正格)의 보혈(補穴) 배신정격(配腎正格)의 보혈(補穴) 및 심정격(心正格) 자침(刺鍼)이 실험적(實驗的) 뇌허혈(腦虛血)에 미치는 영향(影響)

  • Hwang, Moon-Yeon (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Youn, Dae-Hwan (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Na, Chang-Su (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University)
  • 황문현 (동신대학교 한의과대학 경혈학교실) ;
  • 윤대환 (동신대학교 한의과대학 경혈학교실) ;
  • 나창수 (동신대학교 한의과대학 경혈학교실)
  • Published : 2005.12.27

Abstract

Objectives : The acupuncture has been used as treatment of disease in the oriental medicine. In this study, it was investigated at had an effects of Heart JEONGGYEOK(心正格) of SAAM five evolutive phase acupuncture techniques(舍岩五行鑛法) for appling deficiency in the heart induced by experimental focal ischemia. Materials and methods : The focal ischemia was induced by middle cerebral artery occlusion for 2hours. The groups divided into 6 groups, normal(intactness group), control(no therapy group after ischemia-induced), AT1(reinforcing acupoint of Heart JEONGGYEOK : acupuncture therapy group at LR1, HT9 after ischemia-induced), AT2(reinforcing acupoint of Kidney JEONGGYEOK : acupuncture therapy group at LU8, KI7 after ischemia-induced) AT3(combination of reinforcing acupoint of Heart JEONGGYEOK and Kidney JEONGGYEOK : acupuncture therapy group at LR1, HT9, LU8, KI7 after ischemia-induced) AT4(reinforcing and reducing acupoint of Heart JEONGGYEOK : acupuncture therapy group at LR1, HT9, HT3, KI10 after ischemia-induced), AT4(reinforcing and reducing acupoint of Heart JEONGGYEOK : acupuncture therapy group at LRI, HT9, HT3, KI10 after ischemia-induced). Acupuncture therapy was carried out during 3 weeks after focal ischemia-induced. Eight-arm radial maze was used for the behavioral task and neuropretective effect of acupuncture therapy was observed by Cresyl violet, AchE, ChAT-stain. Results : The error rate in the eight-arm radial maze task was significantly decreased in AT3 group on 3days, in AT1 and AT4 groups on 4days, in AT3 and AT4 groups on 5days compared to the control group. The rate of correct choice was significantly increased AT4 group compared to the control group. The density of neurons in the hippocampal CA1 were significantly increased in all experiment groups, AT1, AT2, AT3 and AT4 groups compared to the control group. The density of AchE in the hippocampal CA1 was significantly increased in AT4 group compared to the control group. The density of ChAT in the hippocampal CA1 were significantly increased in AT1 and AT3 group compared to the control group. Conclusions : These results suggest that reinforcing and reducing acupoint of Heart JEONGGYEOK could be used as a medication for controlling the stroke by deficiency in the heart.

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