Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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In vitro Antioxidant Activity of Ethanolic Extract of Chlorophytum borivilianum

  • Govindarajan, R. (Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute) ;
  • Sreevidya, N. (Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute) ;
  • Vijayakumar, M. (Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute) ;
  • Thakur, M. (Pharmacognosy Division, Department of Pharmaceutical Sciences) ;
  • Dixit, V.K. (Pharmacognosy Division, Department of Pharmaceutical Sciences) ;
  • Mehrotra, S. (Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute) ;
  • Pushpangadan, P. (Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute)
  • Published : 2005.09.01
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Abstract

Chlorophytum borivilianum Baker (Antharicaceae) commonly referred as 'Safed Musli' has been widely used in the Indian traditional systems of medicine to treat various diseases like rheumatism apart from having immunomodulating property and is used as general tonic. It is also known as 'Ayurvedic viagra' for its aphordisiac properties. C. borivilianum was screened for the first time to determine its antioxidant activity, isolation of the sapogenins and standardization of the isolated sapogenin fraction using HPTLC. Potent antioxidant activity of ethanolic extract was found by their ability to scavenge DPPH (84.51%), hydroxyl radical (48.95 %), ferryl bi-pyridyl complex (84.53%) along with the inhibition of lipid peroxidation (67.17%) at $100\;{\mu}g/ml$ concentration. The ethanolic extract also exhibited significant inhibition of superoxide anion radical generated by photochemiluminescence. Thus, the potent antioxidant activity validates the innumerable therapeutic claims of the plant in the traditional system especially its use as a Rasayana drug.

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References

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