The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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The Effects of Gudambopae-Tang on Changes of Cytokines in Allergic Rhinitis Model

거담보폐탕(去痰補肺湯)이 알레르기성 비염 모델 생쥐의 cytokine변화에 미치는 영향

  • Yang, Hee-Yeon (Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology College of Oriental Medicine, Kyunghee University) ;
  • Kim, Yoon-Bum (Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology College of Oriental Medicine, Kyunghee University)
  • 양희연 (경희대학교 한의과대학 안이비인후피부과학교실) ;
  • 김윤범 (경희대학교 한의과대학 안이비인후피부과학교실)
  • Published : 2005.08.25
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Abstract

In order to investigate the effects of Gudambopae-Tang on allergic rhinitis, laboratory study about cytokines and OVA-specific IgE was perfomed in the present study. The results are summarized as follow; 1. IL4, IL-5 was increased in medicating group than control group. 2. $IFN-{\gamma}$ was increased in medicating group than control group. 3. total IgE and OVA-specific IgE was significant decreased in medicating group than control group, statistically significant. This study shows experimentally that Gudambopae-tang could reduce allergic reaction in allergic rhinitis. Advanced studies are required to investigate the mechanisms of herbal medicine in allergic rhinitis model.

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