참고문헌
- Bhattacharya, R. K. and Firozi, P. F., Effect of plant flavonoids on microsome catalyzed reactions of aflatoxin B1 leading to activation and DNA adduct formation. Cancer Letter, 39, 85-91 (1988) https://doi.org/10.1016/0304-3835(88)90043-2
- Buckley, M. M.-T., Grant, S. M., Goa, K. L., McTabish, D., and Sorkin, E. M., Diltiazem: A reappraisal of its pharmacological properties and therapeutic use. Drugs, 39, 757-806 (1990) https://doi.org/10.2165/00003495-199039050-00009
- Na, J. H. and Choi, J. S., Effect of naringin on the pharmacokinetics of nifedifine in rabbits. J. Kor. Pharm. Sci., 35, 101-106 (2005)
- Chaffman, M. and Brogden, R. N., Diltiazem: a review of its pharmacological properties and therapeutic efficacy. Drugs, 29, 387-454 (1985) https://doi.org/10.2165/00003495-198529050-00001
- Choi, J. S., Choi, B. C., and Choi, K. E., Effect of quercetin on the pharmacokinetics of oral cyclosporine. Am. J. Health Syst. Pharm., 61, 2406-2409 (2004)
- Choi, J. S., Jo, B. W., and Kim, Y. C., Enhanced paclitaxel bioavailability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin. Eur. J. Pharm. Biopharm., 57, 313-318 (2004) https://doi.org/10.1016/j.ejpb.2003.11.002
- Choi, J. S. and Han, H. K., The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil, in rabbits. J. Pharm. Pharmacol., 56, 1537-1542 (2004) https://doi.org/10.1211/0022357044814
- Choi, J. S. and Shin, S. C., Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats. Int. J. Pharm., 292, 149-156 (2005) https://doi.org/10.1016/j.ijpharm.2004.11.031
- Dixon, R. A. and Steele, C. L., Flavonoids andisoflavonoids-a gold mine for metabolic engineering. Trends Plant Sci., 4, 394-400 (1999) https://doi.org/10.1016/S1360-1385(99)01471-5
- Dupuy, J., Larrieu, G., Sutra, J. F., Lespine, A., and Alvinerie, M., Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin. Vet. Parasitol., 112, 337-347 (2003) https://doi.org/10.1016/S0304-4017(03)00008-6
- Fang, S. H., Hou, Y. C., Chang, W. C., Hsiu, S. L., Chao P. D., and Chiang, B. L., Morin sulfates/glucuronides exert antiinflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci., 74, 743- 756 (2003) https://doi.org/10.1016/j.lfs.2003.07.017
- Fraile, L. J., Aramayona, J. J., Bregante, M. A., Garcia, M. A., and Aradia, A. R., Deacetylation of diltiazem by several rabbit tissues. Pharm. Res., 13. 1875-1880 (1996) https://doi.org/10.1023/A:1016049628453
- Francis, A. R., Shetty, T. K., and Bhattacharya, R. K., Modulating effect of plant flavonoids on the mutagenicity of N-methyl-N-nitro-N-nitrosoguanidine. Carcinogenesis, 10, 1953-1955 (1989) https://doi.org/10.1093/carcin/10.10.1953
- Goebel, K. J. and Kolle, E. U., High performance liquid chromatographic dertermination of diltiazem and four of its metabolites in plasma. J. Chromatogr., 345, 355-363 (1985) https://doi.org/10.1016/0378-4347(85)80172-9
- Gottesman, M. M. and Pastan, I., Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem., 62, 385-427 (1993) https://doi.org/10.1146/annurev.bi.62.070193.002125
- Hanasaki, Y., Ogawa S., and Fukui, S., The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic. Biol. Med., 16, 845-850 (1994) https://doi.org/10.1016/0891-5849(94)90202-X
- Han, H. K. and Choi, J. S., Enhanced diltiazem bioavailability after oral administration of diltiazem with naringin in rats. Int. J. Pharm., Submitted for publication (2005)
- Hodek, P., Trefil, P., and Stiborova, M., Flavonoids-potent and versaltile biologically active compounds interacting with cytochromes P450. Chem. Biol. interact., 139, 1-21 (2002) https://doi.org/10.1016/S0009-2797(01)00285-X
- Homsy, W., Caille, G., and du Souich, P., The site of absorption in the small intestine determines diltiazem bioavailability in the rabbit. Pharm. Res., 12, 1722-1726 (1995a) https://doi.org/10.1023/A:1016217822770
- Homsy, W., Lefebvre, M., Caille, G., and du Souich, P., Metabolism of diltiazem in hepatic and extrahepatic tissues of rabbits: in vitro studies. Pharm. Res., 12, 609-614 (1995b) https://doi.org/10.1023/A:1016226601988
- Kim, H. K., Cheon, B. S., Kim, Y. H., Kim S. Y., and Kim, H. P., Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure-activity relationships. Biochem. Pharmacol., 58, 759-765 (1999) https://doi.org/10.1016/S0006-2952(99)00160-4
- Kim, H. S., Choi, J. S., and Choi, I., Effect of naringin on tamoxifen pharmacokinetics in rats. Kor. J. Clin. Pharm., 15, 55-60 (2005)
- Kim, H. J. and Choi, J. S., Effect of pretreatmemt of naringin on the bioavailability of diltiazem and deacetylditiazem in rabbits. Yakhak Hoeji, 49, 230-236 (2005)
- Kok, L. D., Wong, Y. P., Wu, T. W., Chan, H. C., Kwok, T. T., and Fung, K. P., Morin hydrate: a potential antioxidant in minimizing the free-radicals-mediated damage to cardiovascular cells by anti-tumor drugs. Life Sci., 67, 91-99 (2000) https://doi.org/10.1016/S0024-3205(00)00605-6
- Kolars, J. C., Schmiedlin-Ren, P., Dobbins, W. O. 3rd, Schuetz, J., Wrighton, S. A., and Watkins, P. B., Heterogeneity of cytochrome P450IIIA expression in rat gut epithelia. Gastroenterology, 102, 1186-1198 (1992) https://doi.org/10.1016/0016-5085(92)90756-O
- Lefebvre, M., Homsy, W., Caille, G., and du Souich, P., Firstpass metabolism of diltiazem in anesthetized rabbits: role of extrahepatic organs. Pharm. Res.,13, 124-128 (1996) https://doi.org/10.1023/A:1016097805003
- Li, X. and Choi, J. S., Enhanced diltiazem bioavailability after oral administration of diltiazem with quercetin to rabbits. Int. J. Pharm., 297, 1-8 (2005) https://doi.org/10.1016/j.ijpharm.2004.12.004
- Molden, E., Asberg, A., and Christensen, H., CYP2D6 is involved in O-demethylation of diltiazem-an in vitro study with transfected human liver cells. Eur. J. Clin. Pharmacol., 56, 575-579 (2000a) https://doi.org/10.1007/s002280000182
- Molden, E., Christensen, H., and Sund, R. B., Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro. Drug Metab. Dispos., 28, 107-109 (2000b)
- Nguyen, H., Zhang, S., and Morris, M. E., Effect of flavonoids on MRP1-mediated transport in Panc-1 cells. J. Pharm. Sci., 92, 250-257 (2003) https://doi.org/10.1002/jps.10283
- Pichard, L. G., Gillet, G., Fabre, I., Dalet-Beluche, I., Bonfils, C., and Thenot, J. P., et al., Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem. Drug Metab. Dispos.,18, 711- 719 (1990)
- Pool, P. E., Diltiazem. In: F. H. Messerli Editor, Cardiovascular Drug Therapy (2nd ed.) Saunders Philadelphia, pp. 931-971, (1996)
- Ramanathan, L., Das, N. P., and Li, Q. T., Studies on lipid oxidation in fish phospholipid liposomes. Biol. Trace Elem. Res., 40, 59-70 (1994) https://doi.org/10.1007/BF02916821
- Raso, G.M., Meli, R., Di Carlo, G., Pacilio, M., and Di Carlo, R., Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1. Life Sci., 68, 921-931 (2001) https://doi.org/10.1016/S0024-3205(00)00999-1
- Rocci, M.L. and Jusko, W.J., LAGRAN program for area and moments in pharmacokinetic analysis. Computer Programs in Biomedicine, 16, 203 (1983) https://doi.org/10.1016/0010-468X(83)90082-X
- Saeki, T., Ueda, K., Tanigawara, Y., Hori, R., and Komano,T., Pglycoprotein- mediated transcellular transport of MDRreversing agents. FEBS Lett., 324, 99-102 (1993) https://doi.org/10.1016/0014-5793(93)81540-G
- Vaclavikova, R., Horsky, S., Simek, P., and Gut, I., Paclitaxel metabolism in rat and human liver microsomes is inhibited by phenolic antioxidants. Naunyn. Schmiedebergs. Arch. Pharmacol., 368, 200-209 (2003) https://doi.org/10.1007/s00210-003-0781-9
- Wacher, V. J., Salphati, L., and Benet, L. Z., Active secretion and enterocytic drug metabolism barriers to drug absorption. Adv. Drug Deliv. Rev., 46, 89-102 (2001) https://doi.org/10.1016/S0169-409X(00)00126-5
- Watkins, P. B., Wrighton, S. A., Schuetz, E. G., Molowa, D. T., and Guzelian, P. S., Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J. Clin. Invest., 80, 1029-1036 (1987) https://doi.org/10.1172/JCI113156
- Weir, M. R., Diltiazem: ten years of clinical experience in the treatment of hypertension. J. Clin. Pharmacol., 35, 220-232 (1995) https://doi.org/10.1002/j.1552-4604.1995.tb04051.x
- Yeung, P. K., Feng, J. D. Z., and Buckley, S. J., Pharmacokinetics and hypotensive effect of diltiazem in rabbits: Comparison of diltiazem with its major metabolites. J. Pharm. Pharmacol., 50, 1247-1253 (1998) https://doi.org/10.1111/j.2042-7158.1998.tb03341.x
- Yusa, K. and Tsuruo, T., Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to Pglycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells. Cancer Res., 49, 5002-5006 (1989)
- Zhang, S. and Morris, M. E., Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J. Pharmacol. Exp. Ther., 304, 1258-1267 (2003) https://doi.org/10.1124/jpet.102.044412