Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
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The Effects of Monacolin - Inoculated Rice Embryo on the Body Fat and Serum Lipid Profiles of Obese Elementary School Students

홍국균접종 쌀배아 섭취가 중등도 비만 초등학생의 체지방 및 혈중지질의 개선에 미치는 영향

  • Kang Soon Ah (Department of Molecular Biotechnology, BMIC, Konkuk University) ;
  • Kwoun Soon-Ju (Department of Applied Biology and Chemistry Konkuk University) ;
  • Choi Young-Sook (Department of Laboratory Medicine, College of Medicine, Konkuk University Hospital) ;
  • Lim Yoongho (Department of Applied Biology and Chemistry Konkuk University) ;
  • Park Dong Ki (Department of Applied Biology and Chemistry Konkuk University)
  • 강순아 (건국대학교 분자생명공학과 생명분자정보학센터) ;
  • 권순주 (건국대학교 응용생물화학과) ;
  • 최영숙 (건국대학교 의과대학 임상병리과학교실) ;
  • 임융호 (건국대학교 응용생물화학과) ;
  • 박동기 (건국대학교 응용생물화학과)
  • Published : 2005.10.01
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Abstract

The purpose of this study was to investigate the effect of Monacolin-inoculated rice embryo on the body fat and serum lipid profiles in 61 obese elementary school students. The subjects divided into two groups 31 obese children had the experimental diet (rice embryo inoculated Monacolin) and 30 obese children had the control diet three times a day after meals. The mean age, height, weight, and BMI of 61 subjects were $10.5\pm0.5$ years, $143.6\pm6.8cm,\;55.0\pm8.9kg,\;and\;26.1 \pm3.9$, respectively. The changes of body fat mass (kg) in experimental group and control group after 6 weeks were -0.60kg and -0.03kg, respectively. The changes of body fat $(\%)$ in experimental group and control group after 6weeks were $-1.44\%\;and\;-0.25\%$, respectively. These changes of body fat in experimental group were significantly higher than in control group (p<0.05). The change of total-cholesterol in experimental group and control group during 6weeks were -17.52mg/dL and -1.70mg/dL, respectively. The change of LDL-cholesterol in experimental group and control group during 6 weeks were -17.06mg/dL and - 2.80mg/dL, respectively. The change of triglyceride in experimental group and control group after 6 weeks were -9.58mg/dL and 11.67mg/dL. Total-cholesterol, LDL- cholesterol and triglyceride of experimental group after 6 weeks significantly decreased compared to control group (p<0.05). After experimental diet (6 weeks), total-cholesterol was negatively correlated with body water contents, soft lean mass and fat free mass (p<0.05). Triglyceride showed a significantly positive correlation with body weight and body fat mass, however, it was negatively correlated with fat free mass (p<0.05). HDL-cholesterol showed a significantly positive correlation with fat free mass (p<0.05). These results show that Monacolin-inoculated rice embryo is effective in decreasing body fat and blood lipid in obese children.

Keywords

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