Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
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The Effect of Low-power Laser on the Murine Hair Growth

저출력 레이저가 마우스 모발성장에 미치는 영향

  • Chung, Phil Sang (Medical Laser Research Center, Dankook University) ;
  • Kim, Jin Wang (Department of Plastic Surgery, Laser Center, Hallym University) ;
  • Lee, Jeong Ok (Department of Dermatology, Hallym University) ;
  • Ree, Chung Ku (Medical Laser Research Center, Dankook University) ;
  • Oh, Chung Hoon (Medical Laser Research Center, Dankook University) ;
  • Kim, You Chan (Medical Laser Research Center, Dankook University) ;
  • Chung, Sang Woon (Medical Laser Research Center, Dankook University)
  • 정필상 (단국대학교 의학레이저 연구센터) ;
  • 김진왕 (한림의료원 미용성형센터 레이저의학연구소) ;
  • 이정옥 (한림대학교 의과대학 피부과학교실) ;
  • 이정구 (단국대학교 의학레이저 연구센터) ;
  • 오충훈 (단국대학교 의학레이저 연구센터) ;
  • 김유찬 (단국대학교 의학레이저 연구센터) ;
  • 정상운 (단국대학교 의학레이저 연구센터)
  • Received : 2004.09.24
  • Published : 2005.03.10
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Abstract

Low-power laser(LPL) delivers a small amount of energy without elevation of tissue temperature. LPL has been reported to have biostimulation effects including anti-inflammatory, analgesic, regenerative, immunocorrective, and vasodilative effects. However, the effect of LPL on hair growth has rarely been studied. We investigated the effect of LPL on hair growth in the mouse. After depilation of back skin of mice, we classified the mice into 4 groups: control, laser irradiated group, $MoandMore^{(R)}$ applied group, and Spella $707^{(R)}$ applied group. Laser irradiation or application of these drugs were performed on the back skin of the mice for 30 days. The results are summarized as follows. Hair growth of control was first observed at 13 days after depilation, and complete hair regrowth was observed at 25 days. Hair growth of both laser irradiation group and $MoandMore^{(R)}$ applied group was first observed at 9 days after depilation, and complete hair regrowth was observed at 20 days. Hair growth of Spella $707^{(R)}$ applied group was firstly observed at the 9 days after depilation, and complete hair regrowth was observed at the 15 days. Hair growth started at the irradiation site in the laser irradiation group, but it started at the random sites in other groups. In conclusion LPL irradiation have a stimulating effect on the hair growth in the mouse.

Keywords

Acknowledgement

Supported by : 한국과학재단

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