한국재료학회지 (Korean Journal of Materials Research)

  • 제15권8호
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  • Pages.521-527
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  • 2005
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  • 1225-0562(pISSN)
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  • 2287-7258(eISSN)
한국재료학회 (Materials Research Society of Korea)
권호 표지
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플라즈마 중합 처리된 중공사 막의 혈액 적합성

Blood Compatibility of Hollow Fiber Membranes Treated with Plasma Polymerization

  • 권오성 (전북대학교 신소재공학부) ;
  • 이삼철 (한려대학교 신소재공학과)
  • Kwon O. S. (School of Advanced Materials Eng., Chonbuk Nat. Univ.) ;
  • Lee S. C. (Dept. of Advanced Materials Eng., Hanlyo University)
  • 발행 : 2005.08.01
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초록

Surface modification of polypropylene hollow fiber membranes was peformed in order to develop blood-compatible biomaterials for use in the blood contacting and oxygenation membranes of a lung-assist device(LAD). Blood compatibility was determined by using anticoagulation blood and evaluating formation of blood clots on their surfaces as well as activation of plasma coagulation cascade, platelet adhesion, and aggregation. It was verified that the number of platelets on the silicone coated fibers was significantly lower than those on polypropylene. It was also found that the polypropylene hollow fiber membranes using plasma treatment exhibited suppression of complement activation in blood compatibility test.

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참고문헌

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