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생체유사환경에서 성장된 아파타이트 층의 나노구조 연구

Nanostructural Study of Apatite Film Biomimetically Grown in SBF (Simulated Body Fluid)

  • 김정 (충남대학교 금속공학과) ;
  • 이갑호 (충남대학교 금속공학과) ;
  • 홍순익 (충남대학교 금속공학과)
  • Kim, Joung (Department of Metallugical Engineering, Chungnam National University) ;
  • Lee, Kap-Ho (Department of Metallugical Engineering, Chungnam National University) ;
  • Hong, Sun-Ig (Department of Metallugical Engineering, Chungnam National University)
  • 발행 : 2005.11.01

초록

The ultrastructure ore of a nanostructured apatite film nucleated from solution was studied to gain insights into that of bone minerals which is the most important constituent to sustain the strength of bones. Needle-shaped apatite crystal plates with a bimodal size distribution $(\~100\;to\;\~1000 nm)$ were randomly distributed and they were found to grow parallel to the c-axis ([002]), driven by the reduction of surface energy. Between these randomly distributed needle-shaped apatite crystals which are parallel to the film, apatite crystals (20-40nm) with the normal of the grains quasi-perpendicular to the c-axis were observed. These observations suggest that the apatite film is the interwoven structure of apatite crystals with the c-axis parallel and quasi-perpendicular to the fan. In some regions, amorphous calcium phosphate, which is a precursor of apatite, was also observed. In the amorphous phase, small crystalline particle with the size of 2-3 nm were observed. These particles were quite similar, in size and shape, to those observed in the femoral trabecular bone, suggesting the nucleation of apatites by a biomimetic process in vitro is similar to that in vivo.

키워드

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