Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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A Case of Recurrent Dermatofibrosarcoma of the Scalp

  • Jo, Tae-Yeon (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital) ;
  • Kim, Sang-Dae (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital) ;
  • Kim, Se-Hoon (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital) ;
  • Park, Jung-Yul (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital)
  • Published : 2005.03.31
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Abstract

We report a case of recurrent dermatofibrosarcoma in a 30-years-old woman who had undergone operations three times during 60 months and had received post-operative radiotherapy. On neurological examination, no neurological deficits were noticed. In brain magnetic resonance image(MRI), there was right parieto-occipital scalp mass with high signal in T2-weighted image, low signal in T1-weighted image with homogeneous enhancement. The removal was done including about 2cm uninvolved margins and pathologic examination of the lesion revealed dermatofibrosarcoma protuberans(DFSP). The prognostic factors of local recurrence may be related to surgical margins for resection; the length from the grossly intact margins, and the microscopically controlled excision in margins.

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References

  1. Ballo MT, Zagars GK, Pisters P, Pollack A : The role of radiation therapy in the management of dermatofibrosarcoma protuberans. Int J Radiat Oncol Biol Phys 40 : 823-827, 1998 https://doi.org/10.1016/S0360-3016(97)00895-X
  2. Bowne WB, Antonescu CR, Leung DHY, Katz SC, Hawkins WG, Woodruff JM, et al : Dermatofibrosarcoma protuberans : a clinicopathologic analysis of patients treated and followed at a single institution. Cancer 88 : 2711-2720, 2000 https://doi.org/10.1002/1097-0142(20000615)88:12<2711::AID-CNCR9>3.0.CO;2-M
  3. D'Andrea F, Vozza A, Brongo S, Di Girolamo F, Vozza G : Dermatofibrosarcoma protuberans : experience with 14 cases. J Eur Acad Dermatol Venereol 15 : 427-429, 2001 https://doi.org/10.1046/j.0926-9959.2001.00307.x
  4. Das L, Grover SB, Chand K, Dawson L : Intracranial extension of a dermatofibrosarcoma protuberans of the scalp : a case report with brief review of literature. Surg Neurol 54 : 452-454, 2000 https://doi.org/10.1016/S0090-3019(00)00297-4
  5. Domanski HA, Gustafson P : Cytologic features of primary, recurrent, and metastatic dermatofibrosarcoma protuberans. Cancer 96 : 351- 361, 2002 https://doi.org/10.1002/cncr.10760
  6. Gloster HM Jr, Harris KR, Roenigk RK : A comparison between Mohs micrographic surgery and wide surgical excision for the treatment of dermatofibrosarcoma protuberans. J Am Acad Dermatol 35 : 82-87, 1996 https://doi.org/10.1016/S0190-9622(96)90159-0
  7. Laskin WB : Dermatofibrosarcoma protuberans. CA Cancer J Clin 42 : 116-125, 1992 https://doi.org/10.3322/canjclin.42.2.116
  8. Oliveira-Soares R, Viana I, Vale E, Soares-Almeida LM, Picoto A : Dermatofibrosarcoma protuberans : a clinicopathological study of 20 cases. J Eur Acad Dermatol Venereol 16 : 441-446, 2002 https://doi.org/10.1046/j.1468-3083.2002.00558.x
  9. Saeki H, Ohmatsu H, Hoashi T, Asano N, Idezuki T, Kawabata Y, et al : Dermatofibrosarcoma protuberans with COL1A1 (exon 18) - PDGFB (exon 2) fusion transcript. Br J Dermatol 148 : 1028-1031, 2003 https://doi.org/10.1046/j.1365-2133.2003.05367.x
  10. Sasaki M, Ishida T, Horiuchi H, Machinami R : Dermatofibrosarcoma protuberans : an analysis of proliferative activity, DNA flow cytometry and p53 overexpression with emphasis on its progression. Pathol Int 49 : 799-806, 1999 https://doi.org/10.1046/j.1440-1827.1999.00944.x
  11. Stojadinovic A, Karpoff HM, Antonescu CR, Shah JP, Singh B, Spiro RH, et al : Dermatofibrosarcoma protuberans of the head and neck. Ann Surg Oncol 7 : 696-704, 2000 https://doi.org/10.1007/s10434-000-0696-3
  12. Sun LM, Wang CJ, Huang CC, Leung SW, Chen HC, Fang FM, et al : Dermatofibrosarcoma protuberans : treatment results of 35 cases. Radiother Oncol 57 : 175-181, 2000 https://doi.org/10.1016/S0167-8140(00)00228-0