The Transactions of the Korean Institute of Electrical Engineers D (대한전기학회논문지:시스템및제어부문D)

The Korean Institute of Electrical Engineers (대한전기학회)
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Treatment for HIV-Infected Patients to Induce Long-Term Non-Progressor with Constant Drug Dosage

일정한 약물 투여를 통한 HIV 감염자의 long-term Non-Progressor 전환 치료

  • 김진영 (한양대 공대 전자전기컴퓨터공학부) ;
  • 김원희 ((주)삼성전자 TN총괄) ;
  • 고지현 (McGill University 의대 신경과학부) ;
  • 정한별 (한양대 공대 전기공학과) ;
  • 정정주 (한양대 공대 전자전기컴퓨터공학부)
  • Published : 2005.04.01
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Abstract

This paper presents a therapy that uses a constant drug dosage for leading HIV-infected patient to LTNP (Long-Term Non-Progressor). Based on analysis of CTLp (Cytotoxic T Lymphocyte precursor) concentration at equilibrium point and its bifurcation, we found the therapy with a drug whose efficacy is less than a certain level brings higher CTLp concentration at the equilibrium point. We observed a treatment with constant drug dosage whose efficacy is less than full treatment may lead HIV-infected patient to LTNP. It turns out that the treatment whose efficacy is less than full treatment is better in the point of performance on controllability.

Keywords

References

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