Advances in Traditional Medicine

  • 제6권3호
  • /
  • Pages.232-236
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  • 2006
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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Hypoglycemic and antihyperglycemic activity of leaf extract of pluchea indica Less

  • Pramanik Kartick Chandra (Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University) ;
  • Bhattacharya Plaban (Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University) ;
  • Biswas Ria (Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University) ;
  • Bandyopadhyay Durba (Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University) ;
  • Mishra Moumita (Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University) ;
  • Chatterjee TK (Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University)
  • 발행 : 2006.09.01
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초록

The hypoglycemic and antihyperglycemic activity of methanolic extract of Pluchea indica Less. (Asteraceae) (MEPI) leaves were studied in normal rats and in streptozotocin induced diabetic rats respectively. The blood glucose levels were measured at 1, 4, 8, 16 and 24 h intervals after the treatment. The MEPI leaves showed reduction in blood glucose level in normal (35.12% and 36.01 % for 200 and 400 mg/kg, p.o. respectively) and in steptozotocin induced diabetic rats (36.10% and 41.87% for 200 and 400 mg/kg respectively). A toxicity study has been performed for the extract, which revealed that the extract is safe to use even at the doses of 3.2 gm/kg of body weight orally.

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참고문헌

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피인용 문헌

  1. (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity vol.2018, pp.1741-4288, 2018, https://doi.org/10.1155/2018/4108787