Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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NMR Data of Flavone Derivatives and Their Anti-oxidative Activities

  • Park, Yeong-Hui (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Lee, Yong-Uk (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Kim, Ho-Jung (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Lee, Young-Shim (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Yoon, Young-Ah (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Mun, Byeong-Ho (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Jeong, Yu-Hun (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • An, Jung-Hun (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Shim, Yhong-Hee (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University) ;
  • Lim, Yoong-Ho (Bio/Molecular Informatics Center, Department of Bioscience and Biotechnology, IBST, Konkuk University)
  • Published : 2006.10.20
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Abstract

The $^1H$ and $^{13}C$ chemical shifts of eleven flavone derivatives were completely determined by basic 1D and 2D NMR experiments. Nineteen flavone derivatives including the above eleven derivatives were examined for anti-oxidative effects using the 1,1-diphenyl-2-picryl-hydrazyl assay and Caenorhabditis elegans. In order to understand the relationships between the structures of flavone derivatives and their anti-oxidative activities, a Comparative Molecular Field Analysis was performed.

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References

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