Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Surgical Lung Biopsy for Diffuse Infiltrative Lung Disease

미만성 침윤성 폐질환의 외과적 폐생검

  • Lee, Jang-Hoon (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Yeungnam University) ;
  • Kwon, Jin-Tae (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Yeungnam University) ;
  • Lee, Jung-Cheul (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Yeungnam University)
  • 이장훈 (영남대학교 의과대학 흉부외과학교실) ;
  • 권진태 (영남대학교 의과대학 흉부외과학교실) ;
  • 이정철 (영남대학교 의과대학 흉부외과학교실)
  • Published : 2006.11.05
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Abstract

Background: The diffuse infiltrative lung disease requires surgical lung biopsy for its final diagnosis. We evaluated the effect of surgical lung biopsy for final diagnosis of duffuse interstitial lung disease and compared video assisted thoracoscopic lung biopsy(TLB) with open lung biopsy(OLB). Material and Method: We evaluated the patients who underwent surgical lung biopsy from March 2000 from December 2005, retrospectively, We divide to two groups(OLB and TLB group) and compared them. Result: There were 36 patients and cough was the most common pre- operative symptom. Surgery time, anesthetic time, hospital stay, duration of chest tube indwelling, specimen volume and the rate of post-operative complication were not significantly different between two groups. Histologic diagnosis was confirmed in all cases. There was one post-operative death who had suffered from respiratory failure since pre-operative period. Conclusion: Surgical lung biopsy is effective method in final diagnosis for diffuse infiltrative lung disease. Video assisted thoracoscopic lung biopsy is lesser invasive method than open lung biopsy and provide similar results, so it is basic diagnostic method of surgical lung biopsy.

배경: 미만성 침윤성 폐질환의 확진을 위해서는 외과적 폐생검이 필요하다. 개흉 폐생검과 흉강경 폐생검 방법을 비교하고 외과적 폐생검이 미만성 간질성 폐질환의 진단에 미치는 영향을 알아보고자 하였다. 대상 및 방법: 2000년 3월부터 2005년 12월까지 영남대학교의료원 흉부외과에서 폐생검을 시행한 환자를 후향적 조사를 하였다. 외과적 폐생검 후 조직학적 진단과 치료방침의 변화를 분석하고 소개흉술을 실시한 군(OLB)과 비디오 흉강경수술을 실시한 군(TLB)으로 나누어 비교 분석하였다. 결과: 전체 환자는 36명이었고 기침이 가장 많은 술 전 증상이었다. OLB군과 TLB군 사이에 수술시간, 마취시간, 재원기간, 흉관거치 기간, 채취한 조직의 용적, 합병증 발생률에는 유의한 차이가 없었다. 전 예에서 술 후 조직학적 진단이 가능하였다. 술 후 33%에서 치료 방침의 변화가 있었고 두 군 간유의한 차이는 없었다. 술 후 사망은 1예가 있었고 술 전 호흡부전이 있었던 환자에서 발생하였다. 결론: 외과적 폐생검은 미만성 침윤성 폐질환을 확진할 수 있는 진단방법이고 술 후 치료 방침의 결정에 많은 도움을 준다. 흉강경 폐생검은 개흉 폐생검에 비해 덜 침습적이고 동일한 조직학적 진단율을 보이므로 외과적 폐생검의 기본 수술술기라 할 수 있다.

Keywords

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