Nutritional Sciences

The Korean Nutrition Society (한국영양학회)
권호 표지

Combined Effects of Cell Cultured Acanthopanax Senticosus Supplementation and Exercise on Lipid Profiles, Carnitine and Leptin Levels in Mice

  • Koo, Bon-Sun (Research Institute Center of Bioactive Material, Chonbuk National University) ;
  • Soh, Ju-Ryoun (Department of Food Science and Human Nutrition, Human Nutrition & Research Institute of Human Ecology, Chonbuk National University) ;
  • Cha, Youn-Soo (Department of Food Science and Human Nutrition, Human Nutrition & Research Institute of Human Ecology, Chonbuk National University)
  • Published : 2006.11.30
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Abstract

The purpose of this study was to determine the independent and the combined effects of cell cultured Acanthopanax senticosus extracts (ASE) supplementation and swimming exercise on body weight, lipid profile, carnitine and leptin levels in C57 BL/6J mice. Forty C57BL/6J mice were divided into four groups: non-supplement and non-exercise (NSNE); non-supplement and exercise (NSE); supplement and non-exercise (SNE); supplement and exercise (SE) mice. They were allowed free access to food and water. The exercised groups were forced to swim (1hr, 6 days a week) in a water bath for 12 weeks. The supplemented groups were fed Cell cultured ASE (0.5 g/kg body weight/day) for 12 weeks. In this study, we found that the combination of Cell cultured ASE supplementation and exercise significantly decreased liver triglyceride (TG) level and serum leptin level but significantly increased serum HDL-cholesterol level compare to control (NSNE) group. These improved lipid profiles and decreased serum leptin would have positive effects on obesity and cardiovascular disease.

Keywords

References

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