Korean Journal of Materials Research (한국재료학회지)

Materials Research Society of Korea (한국재료학회)
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The Influence of β-TCP Content on the Preparation of Biodegradable β-TCP/PLGA Composites Using Microwave Energy

마이크로파에 의한 생분해성 β-TCP/PLGA 복합체의 제조시 β-TCP 첨가량에 따른 영향

  • Jin, Hyeong-Ho (School of Materials Science and Engineering, Pusan National University) ;
  • Min, Sang-Ho (School of Materials Science and Engineering, Pusan National University) ;
  • Park, Hong-Chae (School of Materials Science and Engineering, Pusan National University) ;
  • Yoon, Seog-Young (School of Materials Science and Engineering, Pusan National University)
  • Published : 2006.01.27
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Abstract

Biodegradable $\beta$-tricalcium phosphate ( $\beta$-TCP)/poly(lactide-co-glycolide) (PLGA) composites were synthesized by in-situ polymerization with microwave energy. The influence of the $\beta$-TCP content in $\beta$-TCP/PLGA composites on the molecular weight, crystallinity, microstructure and mechanical properties was investigated. As the molecular weight of composites decreased, the $\beta$-TCP content increased up to 10 wt.%, while the excess addition of the $\beta$-TCP content above 10 wt.% the molecular weight increased with increasing of the $\beta$-TCP content. This behavior would be due to the superheating effect or nonthermal effect induced by microwave energy. It was found that the bending strength and Young's modulus of the $\beta$-TCP/PLGA composites was proportional to the molecular weight of PLGA. The bending strength of the $\beta$-TCP/PLGA composites ranged from 18 to 38 MPa, while Young's modulus was in the range from 2 to 6 GPa.

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References

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