환경위생공학 (Journal of environmental and Sanitary engineering)

대한환경위생공학회 (Korean Society for Environmental Sanitary Engineers)
권호 표지

수종의 버섯 추출물이 티로시나아제 프로모터에 미치는 효과

Effect of Mushroom Extracts on Tyrosinase Promoter

  • 진종언 (동강대학교 피부미용과) ;
  • 이혜성 (동강대학교 피부미용과) ;
  • 김관천 (광주보건대학 환경행정과)
  • 발행 : 2006.09.30
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초록

To estimate the inhibitory effect of some mushroom extract on melanin biosynthesis, we tested its inhibitory effects of five mushroom extracts on tyrosinase promoter in Bl6 mouse melanoma cells. In five mushroom extracts, Cordyceps militaris and Poria cocos exhibited low repression effect on tyrosinase promoter. However, Ganoderma lucidum, Paecilomyces japonicus, Phellinus linteus showed high repression effect, Especially, Paecilomyces japonicus and Phellinus linteus extracts had very higher repression effect approximately $81{\sim}83%\;at\;100{\mu}g/mL$. In the MTT assay, Paecilomyces japonicus and Phellinus linteus extracts exhibited high cytotoxicity. Therefore, repression effect of the extracts were closely connected with cytotoxicity.

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참고문헌

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