Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)
- Volume 10 Issue 2
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- Pages.155-162
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- 2006
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- 1226-6531(pISSN)
Chmical Shift Variation of Bovine Angiogenin Upon Binding with Phosphate ions
- Baek, Sun-Hee (Department of Bioscience and Biotechnology, Bio/informatics center, IBST, Konkuk University) ;
- Kang, Dong-Il (Department of Chemistry, Konkuk University) ;
- Lee, Jee-Young (Department of Bioscience and Biotechnology, Bio/informatics center, IBST, Konkuk University) ;
- Shin, Hang-Cheol (Department of Bioinformatics and Life Science, and CAMDRC, Soongsil University) ;
- Kim, Yang-Mee (Department of Bioscience and Biotechnology, Bio/informatics center, IBST, Konkuk University)
- Published : 2006.12.20
Abstract
Angiogenin is unique among angiogenic molecules in that it is a member of the pancreatic ribonuclease superfamily and, in fact, is a ribonucleolytic enzyme. Its enzymatic activity is extremely weak compared to that of the digestive RNases but is critical for its capacity to induce neovascularization. In this study, we completed the backbone resonance assignment of bovine angiogenin using triple resonance NMR experiments of