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Korean Society for Biochemistry and Molecular Biology (생화학분자생물학회)
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2-D Graphical Representation for Characteristic Sequences of DNA and its Application

  • Li, Chun (Department of Mathematics, Bohai University) ;
  • Hu, Ji (Faculty of Chemistry and Chemical engineering, Bohai University)
  • Received : 2005.12.03
  • Accepted : 2006.02.14
  • Published : 2006.05.31
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Abstract

DNA sequencing has resulted in an abundance of data on DNA sequences for various species. Hence, the characterization and comparison of sequences become more important but still difficult tasks. In this paper, we first give a 2-D ladderlike graphical representation for the characteristic sequences of a DNA sequence, and then construct a 3-component vector, in which the normalized ALE-indices extracted from such three 2-D graphs via D/D matrices are individual components, to characterize the DNA sequence. The examination of similarities/dissimilarities among sequences of the $\beta$-globin genes of different species illustrates the utility of the approach.

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References

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