The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
권호 표지

Postoperative Pain Control with Epidural Meperidine Infusion

경막외강 내 Meperidine 지속 주입에 의한 술 후 통증관리

  • Lim, Tae Ha (Department of Anesthesiology and Pain Medicine, Eulji University School of Medicine) ;
  • Choi, Kyu Taek (Department of Anesthesiology and Pain Medicine, College of Medicine, University of Ulsan)
  • 임태하 (을지의과대학교 마취통증의학교실) ;
  • 최규택 (울산대학교 의과대학 마취통증의학교실)
  • Received : 2006.08.04
  • Accepted : 2006.11.28
  • Published : 2006.12.30
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Abstract

Background: Epidural opioids are commonly used for postoperative analgesia. However, the side effects of epidural opioids include respiratory depression, sedation, pruritus, nausea, vomiting and urinary retention. Meperidine, due to its intermediate lipid solubility and local anesthetic properties, permits postoperative analgesia. The aim of this study was to compare meperidine alone to meperidine coupled with bupivacaine, and to determine the effects of epidural meperidine without bupivacaine, when used for epidural analgesia following hepatectomy abdominal surgery. Methods: Patients received thoracic epidural analgesia with meperidine alone (3.5 mg/ml in saline) or with additional bupivacaine (0.15%) for 2 days after surgery. Postoperative pain was assessed using a visual analog scale (VAS) pain score 2 days after the operation, with the incidence and dose supplementation also evaluated. Postoperative side effects were assessed using a 3 grade system. Results: No significant difference was found between the two groups in terms of age and weight, or in the pain scores, side effects, incidence and dose supplementation. Conclusions: 3.5 mg/ml epidural meperidine at a dose of 2 ml/hr provides effective postoperative analgesia.

Keywords

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