Diagnosis of pemphigus erythematosus in a Jindo dog

진도개에서 홍반천포창(pemphigus erythematosus)의 진단

  • Bhang, Dong Ha (College of Veterinary Medicine, Seoul National University) ;
  • Choi, Ul Soo (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Min Kyu (College of Veterinary Medicine, Seoul National University) ;
  • Choi, Eun Wha (College of Veterinary Medicine, Seoul National University) ;
  • Jung, Yun Chan (College of Veterinary Medicine, Seoul National University) ;
  • Kang, Min-Soo (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Dae-Yong (College of Veterinary Medicine, Seoul National University) ;
  • Hwang, Cheol-Yong (College of Veterinary Medicine, Seoul National University) ;
  • Lee, Chang Woo (College of Veterinary Medicine, Seoul National University) ;
  • Youn, Hwan Young (College of Veterinary Medicine, Seoul National University)
  • Accepted : 2006.05.09
  • Published : 2006.06.30

Abstract

A 6-year-old female Jindo dog weighing 20 kg was presented to the Veterinary Medical Teaching Hospital of Seoul National University for the formation of crust and erosion of the nasal bridge and planum, and for alopecia of ear margin. Erythema, crusts, alopecia and erosions were present in the nasal planum and the bridge of the nose on physical examination. There were no abnormalities on CBC, serum chemistry, and basic dermatologic examination which included skin scraping, bacterial cultures, and fungal cultures. On cytology, the acantholytic cells were surrounded by non-degenerate neutrophils. Biopsy samples obtained from skin lesionswere diagnosedpemphigus erythematosus by histopathology and immunochemical staining. Therefore the dog was initially treated with oral prednisolone as an immunosuppressive dose for tour weeks, but clinical manifestations did not improve so far.

Keywords

References

  1. Griffies JD, Mendelsohn CL, Rosenkrantz WS, Muse R, Boord MJ, Griffin CE. Topical 0.1 % tacrolimus for the treatment of discoid lupus erythematosus and pemphigus erythematosus in dogs. J Am Anim Hosp Assoc 2004, 40, 29-41 https://doi.org/10.5326/0400029
  2. Rosanna M. Canine Pemphigus Complex: Diagnosis and Therapy. Compend Contin Educ Pract Vet 2000, 22, 680-685
  3. Rosanna M. Canine Pemphigus Complex: Pathogenesis and Clinical Presentation. Compend Contin Educ Pract Vet 2000, 22, 568-572
  4. Rosenkrantz WS. Pemphigus: current therapy. Vet Dermatol 2004, 15, 90-98 https://doi.org/10.1111/j.1365-3164.2004.00360.x
  5. Rosenkrantz WS, Griffin CE, Barr RJ. Clinical evaluation of cyclosporine in animal models with cutaneous immune mediated disease and epithelitropic lymphoma. J Am Anim Hosp Assoc 1989, 25, 377-384
  6. Scott DW, Miller WH, Griffin CE. Muller & Kirk's Small Animal Dermatology. 6th ed. pp. 243-244, 681-693, Sanunders, Philadelphia, 2001