DOI QR코드

DOI QR Code

Components of Nutraceutical Value in Physalis minima

  • Misra, L.N. (Central Institute of Medicinal and Aromatic Plants) ;
  • Lal, P. (Department of Chemistry, Guru Jambheshwar University) ;
  • Kumar, D. (Department of Chemistry, Guru Jambheshwar University)
  • Published : 2006.03.01

Abstract

It is of utmost importance to feed the current world population by improving agricultural production with newer varieties of food crops, but what is still more important is to add nutrition into the food. Some of the plants, which are currently growing in the wastelands, contain certain phytochemicals which add to their neutraceutical and health value. These plants contain secondary metabolites which enhance the over all metabolic functions of the body. Withasteroids are one of such phytochemicals. These chemicals are almost exclusively found in plants of the Solanaceae family; one of which, Physalis minima, contains several with asteroids. The aerial parts and roots of P. minima have been found to contain several steroids, identification of which is been discussed in this paper. These with asteroids contribute to the functional value since incorporation of withanolides in the diet may prevent or decrease the growth of tumors in humans.

Keywords

References

  1. Anonymous. 1969. The Wealth of India. CSIR, New Delhi, India. Vol 8, p 37-38
  2. Sinha SC, Ray AB. 1988. Chemical constituents of Physalis minima var. indica. J Indian Chem Soc 65: 740-741
  3. Glotter E, Kirson I, Abrahan A, Sethi PD, Subranian SS. 1975. Steroidal constituent of Physalis minima (solanceae). J Chem Soc Perkin Trans II: 1370-1374
  4. Sahai M, Kirson I. 1984. Withaphysalin D, a new withaphysalin from Physalis minima Linn. Var. indica. J Nat Prod 47: 527-529 https://doi.org/10.1021/np50033a022
  5. Gupta A, Gupta R. 1997. A survey of plants for presence of cholinesterase activity. Phytochemistry 46: 827-831 https://doi.org/10.1016/S0031-9422(97)00393-2
  6. Alluri RR, Miller RJ, Shelver WH, Khalil SKW. 1976. Dihydroxyphysalin B, A new physalin from Physalis minima leaves. Lloydia 39: 405-408
  7. Gottlieb HE, Cojocaru M, Sinha SC, Sahu M, Bagchi A, Ali A, Ray AB. 1987. A withanolide from Physalis minima. Phytochemistry 26: 1801-1804 https://doi.org/10.1016/S0031-9422(00)82292-X
  8. Subramanian SS, Sethi PD. 1971. Bitter principles of Physalis minima and Physalis peruviana. Curr Sci 40: 85-86
  9. Kawai M, Makino B, Yamamura H, Batsugah Y. 1996. Upon 'physalin L' isolated from Physalis minima. Phytochemistry 43: 651-663
  10. Glotter E. 1991. Withanolides and related ergostane-type steroids. Nat Prod Rep 4: 415-440
  11. Ray AB, Gupta M. 1994. Withasteroids, a growing group of naturally occurring steroidal lactones. In Progress in the Chemistry of Organic Natural Products. Springer, New York. Vol 63, p 2-106
  12. Anjaneyulu ASR, Rao DS. 1997. New withanolides from the roots of Withania somnifera. Indian J Chem 36B: 424-433
  13. Subramanian SS, Sethi PD, Glotter E, Kirson I, Lavie D. 1971. 5,20${\alpha}$(R)-Dihydroxy-6${\alpha}$,7${\alpha}$-epoxy-1-oxo-(5${\alpha}$) with- 2,24-dienolide, a new steroidal lactone from Withania coagulans. Phytochemistry 10: 685-688 https://doi.org/10.1016/S0031-9422(00)94725-3
  14. Fuska J, Prousek J, Rosazza J, Budesinsky M. 1982. Microbial transformations of natural antitumor agents. 23. Conversion of withaferin-A to 12${\beta}$- and 15${\beta}$-hydroxy derivatives of withaferin A. Steriods 40: 157-169 https://doi.org/10.1016/0039-128X(82)90030-7
  15. Nair MG, Jayaprakasam B. 2003. Cyclooxygenase-2 enzyme inhibitory withanolides from Withania somnifera leaves. Tetrahedron 59: 841-849 https://doi.org/10.1016/S0040-4020(02)01601-0
  16. Jayaprakasam B, Zhang Y, Seeram NP, Nair MG. 2003. Growth inhibition of human tumor cell lines by with-anolides from Withania somnifera leaves. Life Sciences 74: 125-132 https://doi.org/10.1016/j.lfs.2003.07.007

Cited by

  1. New sucrose esters from the fruits of Physalis solanaceus vol.352, 2012, https://doi.org/10.1016/j.carres.2012.02.003
  2. Isolation and Characterization of Steroids of Nutraceutical Value in Physalis minima vol.11, pp.2, 2006, https://doi.org/10.3746/jfn.2006.11.2.133