Risk Relationship of Cataract and Epilation on Radiation Dose and Smoking Habit

  • Tomita, Makoto (Department of Information Systems and Mathematical Sciences, Nanzan University) ;
  • Otake, Masanori (Department of environmental and mathematical Sciences, Faculty of Environmental Sciences and Technology, Okayama University) ;
  • Moon, Sung-Ho (Department of Statistics, Pusan University of Foreign Studies)
  • Published : 2006.11.30

Abstract

An analytic approach that provides explicit estimates of risk on cataract and epilation data is evaluated by reasonableness of conceivable relative risk models regarding a simple, odds, logistic or Gompertz regression method, assuming a binomial distribution. In these analyses, we apply relative risk models with two thresholds between epilators and nonepilators from a highly characteristic lesion of which radiation cataract does not occur around 2 gray for a single acute exposure. The risk models are fitted to the data assuming 10 as a constant relative biological effectiveness of neutron. The likelihood of observing the entire data set in these models fitted is evaluated by an individual binary-response array. Estimation of a threshold with or without severe epilation and the 100 ($1-\alpha$)% confidence limits are derived from the maximum likelihood approach. The relative risk model with two thresholds can be expressed as a formula with structure of Background $\times$ RR, where RR includes threshold models with or without epilation. The radiosensitivity of ionizing radiation to cataracts has been examined for the relationship between epilators and nonepilators.

Keywords