Effects of Cellulose and Pectin on Postprandial Blood Glucose and Plasma Lipid Concentration

셀룰로오스 및 펙틴이 식후 혈당과 혈장 지질 농도에 미치는 영향

  • Lee Sun-Woo (Department of Food and Nutrition, College of Human Ecology, Chonnam National University) ;
  • Ro Hee-Kyong (Department of Food Science, Dongshin University) ;
  • Choi In-Seon (Department of Food and Nutrition, College of Human Ecology, Chonnam National University) ;
  • Oh Seune-Ho (Department of Food and Nutrition, College of Human Ecology, Chonnam National University)
  • 이선우 (전남대학교 생활과학대학 식품영양학과) ;
  • 노희경 (동신대학교 식품과학과) ;
  • 최인선 (전남대학교 생활과학대학 식품영양학과) ;
  • 오승호 (전남대학교 생활과학대학 식품영양학과)
  • Published : 2006.04.01

Abstract

The purpose of this study was to observe the effects of cellulose and pectin on glucose and plasma lipid concentrations in healthy women. Eight female collage students were participated voluntarily. All subjects received a fiber-free control diet (CD), cellulose diet (CED), pectin diet (PTD) with each diet for a period of three days with a 4 day interval. The food intake of subjects were monitored every day and plasma level of glucose, triglyceride, total cholesterol were determined at last day. Blood glucose, plasma triglyceride, total cholesterol were measured at fasting state and 30, 60, 90, 120, and 180 minute after consuming each diet. Plasma glucose concentrations (AUC: Area Under the Curve) of pectin diet was $122.7{\pm}4.0mg/dl$ and that of cellulose diet was $147.6{\pm}8.4mg/d$, but they were significantly lower than in comparison with those of control diet ($197.1{\pm}11.6mg/dl$) (p<0.05) Plasma triglyceride concentrations of the CED ($-83.9{\pm}22.2mg/dl$) PTD ($-9.7{\pm}26.1mg/dl$) showed gradual decrease after each test diet feeding but not significantly different in each dietary fiber added diet (p<0.05). Plasma cholesterol concentrations of the CD was not significantly different in PTD, but PTD was significantly lower than the CED until 3 hours after consuming each test meal (p<0.05). In conclusion, in spite of total cholesterol was reduced only by pectin, glucose and triglyceride were lower than control diet in dietary fiber intake. But there were no significant differences each dietary fiber.

Keywords

References

  1. Salmeron J, Manson JE, Stampfer MJ, Colditz G, Wing AL, Willett WC. Dietary fiber, glycemic load, and risk of non-insulindependent diabetes mellitus in women. JAMA 277(6): 472-476, 1997 https://doi.org/10.1001/jama.277.6.472
  2. Vuksan V, Korsic M, Posavi AA. Metabolic diseases and the highfiber diet. Lijec Vjesn 119: 125-127, 1997
  3. Rocio A, Daniel ADL, Olatz I, Ternando LC, Lourdes DO, Luis F, Tersa A, Gonzalez H. Effects of soluble fiber intake in lipid and glucose levels in healthy subjects: a randomized clinical trial. Diabetes Res Clin Prac 65(1): 7-11, 2004 https://doi.org/10.1016/j.diabres.2003.11.005
  4. Jue Li, Takashi K, Li-Qiang Q, Jing W, Yuan W. Effects of barley intake on glucose tolerance, lipid metabolism, and bowel function in women. J Nutr 19(11-12): 926-929, 2003 https://doi.org/10.1016/S0899-9007(02)00837-7
  5. Park SH, Lee YK, Lee HS. The effects of dietary fiber feeding on gastrointestinal functions and lipid and glucose metabolism in streptozotocin-induced diabetic rats. Korean J Nutr 27(4): 311-322, 1994
  6. Trowell HC. Definitions of fiber, Lancet 1: 503, 1974
  7. Marlett JA. Dietary fiber, definition and determination, Center for Academic Publication, Japan, pp.4-14, 1990
  8. Helena GML, Anna KEF, Inger MEB. Effects of the glycemic index and content of indigestible carbohydrate of cereal-based breakfast meals on glucose tolerance at lunch in healthy subjects. Am J Clin Nutr 69(4): 647-655, 1999 https://doi.org/10.1093/ajcn/69.4.647
  9. Torsdottir J, Alpsten M, Holm G, Sandberg AS, Tolli J. A small dose of soluble alginate fiber affects postprandial glycemia and gastric emptying in humans with diabetes. J Nutr 121(6): 795-799, 1991
  10. Oku T. New viewpoint on physiological property of dietary fiber and the status of the dietary fiber intakes in Japan. Kor J Nutr 25(2): 77-90, 1992
  11. Gray DS. The clinical uses of dietary fiber. Am Fam Physician 51(2): 419-426, 1995
  12. Lee YK, Lee HS, Kim BY. Effect of short-term feeding of dietary fiber supplements on lipid metabolism in subjects with non- insulindependent diabetes mellitus. Korean J Nutr 19(1): 80-91, 1995
  13. Park SH, Lee YK, Lee HS. The effects of dietary fiber feeding on gastrointestinal functions and lipid and glucose metabolism in streptozotocin-induced diabetic rats. Korean J Nutr 27(4): 311-322, 1994
  14. Nishina PM, Schneeman BO, Freedland RA. Effects of dietary fiber on nonfasting plasma lipoprotein and apolipoprotein levels in rats. J Nutr 121(4): 431-437, 1991 https://doi.org/10.1093/jn/121.4.431
  15. Garcia-Diez F, Garcia-Mediavilla V, Bayon JE, Gonzalez-Gallego J. Pectin feeding influences fecal bile acids excretion, hepatic bile acid and cholesterol synthesis and serum cholesterol in rats. J Nutr 126(7): 1766-1771, 1996
  16. Ahn HS, Kwon JR, Lee SS. Effect of dietary lipids and guar gum on lipid metabolism in ovariectomized rats. Korean J Nutr 30(10): 1123-1131, 1997
  17. Pastors JG, Blaiselell PW, Balm TK, Asplin CM, Pohl SL. Psyllium fiber reduce rise in postprandial glucose and insulin concentrations in patients with non-insulin-dependent diabetes. Am J Clin Nutr 53(6): 1431-1435, 1991 https://doi.org/10.1093/ajcn/53.6.1431
  18. Lee HS, Choi MS, Lee YK, Park SH, Kim YK. Effects of seaweed supplementation on the lipid and glucose metabolism in streptozotocin-induced diabetic rats. Korean J Nutr 29(3): 296- 306, 1996
  19. Rabbo E, Terkidren TC. On the enzymatic determination of blood glucose. Scandinav J Lab Invest 12: 402-407, 1960 https://doi.org/10.3109/00365516009065404
  20. Bucolo G, David H. Quantitative determination of serum triglycerides by use of enzymes. Clin Chem 19: 476-482, 1973
  21. Allain CC, Poon LS, Chen CS, Richmond W. Enzymatic determination of total serum cholesterol. Clin Chem 20: 470-475, 1974
  22. Recommended Dietary Allowances for Koreans. 7th revision, The Korean Nutrition Society, Seoul, 2000
  23. Rosado JL, Diaz M. Physicochemical properties related to gastrointestinal function of 6 sources of dietary fiber. Rev Invest Clin 47(4): 283-289, 1995
  24. Spiller RC. Pharmacology of dietary fiber. Pharmacol Ther 62: 407-427, 1994 https://doi.org/10.1016/0163-7258(94)90052-3
  25. Braaten JT, Scott FW, Wood PJ, Riedel KD, Wolynetz MS, Brule D, Collins MW. High beta-glucan oat bran and oat gum reduce postprandial blood glucose and insulin in subjects with and without type 2 diabetes. Diabet Med 11(3): 312-318, 1994 https://doi.org/10.1111/j.1464-5491.1994.tb00277.x
  26. Qureshi AA, Sami SA, Khan FA. Effects of stabilized rice bran, its soluble and fiber fractions on blood glucose levels and serum lipid parameters in human with diabetes mellitus types I and II. J Nutr Biochem 13(3): 175-187, 2002 https://doi.org/10.1016/S0955-2863(01)00211-X
  27. Lee SH, Park HJ, Cho SY, Jung IK, Cho YS, Kim TY, Hwang HG, Lee TS. Supplementary effect of the high dietary fiber rice on blood glucose in diabetic KK mice. Kor J Nutr 37(2): 75-80, 2004
  28. Williams JA, Lai CS, Corwin H, Ma Y, Maki KC, Garleb KA, Wolf BW. Inclusion of guar gum and alginate into a crispy bar improves postprandial glycemia in humans. J Nutr 134(4): 886-889, 2004
  29. Lee C, Shin JS. Effects of different fiber content of rice on blood glucose and triglyceride levels in normal subject. J Korean Soc Food Sci Nutr 31(6): 1048-1051, 2002 https://doi.org/10.3746/jkfn.2002.31.6.1048
  30. Katri SJ, Leo KN, Kirsi HL, Kaisa SP, Jens JH, Hannu MM. Postprandial glucose, insulin, and incretin responses to grain products in healthy subjects. Am J Clin Nutr 75(2): 254-262, 2002 https://doi.org/10.1093/ajcn/75.2.254
  31. Wolever TMS. Relationship between dietary fiber content and composition in foods and the glycemic index. Am J Clin Nutr 51(1): 72-75, 1990 https://doi.org/10.1093/ajcn/51.1.72
  32. Nishimune T, Yakushiji T, Sumimoto T, Taguchi S, Konishi Y, Nakahara S, Ichikawa T, Kunita N. Glycemic response and fiber content of some foods. Am J Clin Nutr 54(2): 414-419, 1991 https://doi.org/10.1093/ajcn/54.2.414
  33. Lee SH, Park HJ, Cho SY, Han KJ, Jeon HK, Hwang HG, Choe HC. Supplementary effect of the high dietary fiber rice on lipid metabolism in diabetic KK mice. Korean J Nutr 37(2): 81-87, 2004
  34. Song YS, Yang JL, Suh MJ. Effects of dietary fibers on cholesterol metabolism in cholesterol-fed rats. J Korean Soc Food Nutr 25(3): 392-398, 1996
  35. Vigne JL, LaironD, BorelP, Portugal D, Pauli A, Hauton J. Lafont H. Effects of pectin, wheat bran and cellulose on serum lipid and lipoproteins. Br J Nutr 58(3): 405-410, 1987 https://doi.org/10.1079/BJN19870109
  36. Kim MJ, Jang JY, Lee MK, Park JY, Park EM. Effects of fiber lipid concentration in hypercholesterolemic rats. J Korean Soc Food Nutr 12(1): 20-25, 1999
  37. Yun EY, Wang SG. Effects if indigestible dextrin and pectin on lipid metabolism. Kor J Nutr 6(2): 147-154, 1996
  38. Mueller MA, Cleary MP, Kritchevsky D. Influence of dietary fiber on lipid metabolism in meal-fed rats. J Nutr 113(11): 2229-2238, 1983 https://doi.org/10.1093/jn/113.11.2229
  39. Greenwald P, Clifford C. Fiber and cancer: prevention research. In: Dietary fiber in health & disease. Kritchevsky. D, Bonfield, C. eds, Egans, pp.159-173, 1995
  40. Shinnick FL, Ink SL, Marlett JA. Dose response to a dietary oat bran fraction in cholesterol-fed rats. J Nutr 120(6): 561-568, 1990 https://doi.org/10.1093/jn/120.6.561
  41. Katri SL, Kaisa SP, Hunnu MM. Rye bread decreases serum and LDL-cholesterol on men with moderately elevated serum cholesterol. J Nutr 130(2): 164-170, 2000
  42. Ikegami S, Tsuchihashi F, Harada H, Tsuchihashi N, Nishide E, Innami S. Effect of viscous indigestible polysaccharides on pancreatic - biliary secretion and digestive organs in rats. J Nutr 120(4): 353-360, 1990 https://doi.org/10.1093/jn/120.4.353
  43. Park SH, Lee HS. Effects of legume supplementation on the glucose and lipid metabolism and lipid peroxidation in streptozotocin-induced diabetic rats. Korean J Nutr 36(5): 425-436, 2003
  44. Anderson JW, Jones AE, Riddell-Mason S. Ten different dietary fibers have significantly different effects on serum and liver lipids of cholesterol-fed rats. J Nutr 124(1): 78-83, 1994
  45. Jang UK, Yun HJ. Influence of Fat levels and type of dietary fiber on lipid metabolism in rats. Kor J Nutr 17(4): 253-261, 1984
  46. Ehihara K, Schneeman BO. Interaction of bile acids, phospholipid, cholesterol and triglyceride with dietary fiber in small intestine of rats. J Nutr 119(8): 1100-1106, 1989 https://doi.org/10.1093/jn/119.8.1100
  47. Vahouny GV, Roy T, Gallo LL, Story JA, Kritchevsky D, Cassidy MM. Dietary fiber III. Effects of chronic intake on cholesterol absorption and metabolism in the rats. Am J Clin Nutr 33(10): 2182-2191, 1980 https://doi.org/10.1093/ajcn/33.10.2182
  48. Ide T, Horii M, Yamamoto T, Kawashima K. Contrasting effects of water-soluble and water insoluble dietary fiber on bile acid conjugation and taurine metabolism in the rats. Lipids 25(6): 335-340, 1990 https://doi.org/10.1007/BF02544343
  49. Nishina PM. Freedland RA. Effects of propionate on lipid biosynthesis in isolated rat hepatocytes. J Nutr 120(7): 668-673, 1990 https://doi.org/10.1093/jn/120.7.668
  50. Venter CS, Vorster HH, Van Der Nest DG. Comparison between physiological effects of Konjac-glucomannan and propionate in baboons fed 'western' diets. J Nutr 120(9): 1046-1053, 1990 https://doi.org/10.1093/jn/120.9.1046
  51. Anderson JW, Deakins DA, Floore TL, Smith BM, Whitis SE. Dietary fiber and coronary heart disease. Crit Rev Food Sci Nutr 29(2): 95-147, 1990 https://doi.org/10.1080/10408399009527518