Annals of Clinical Neurophysiology
- Volume 8 Issue 1
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- Pages.84-87
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- 2006
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- 2508-691X(pISSN)
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- 2508-6960(eISSN)
Reversible Brain Dysfunction in MELAS Syndrome
가역적인 뇌기능장애를 보인 MELAS 증후군
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Chung, Jin-Seong
(Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
- Lee, Hak-Seung (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
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Park, Hyun-Young
(Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
- Chang, Hyuk (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
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Kim, Yo-Sik
(Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
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Cho, Kwang-Ho
(Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science)
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정진성
(원광대학교 신경과학교실, 원광의과학 연구소) ;
- 이학승 (원광대학교 신경과학교실, 원광의과학 연구소) ;
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박현영
(원광대학교 신경과학교실, 원광의과학 연구소) ;
- 장혁 (원광대학교 신경과학교실, 원광의과학 연구소) ;
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김요식
(원광대학교 신경과학교실, 원광의과학 연구소) ;
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조광호
(원광대학교 신경과학교실, 원광의과학 연구소)
- Published : 2006.06.30
Abstract
The MELAS (Mitochondrial Encephalomyopathy with Lactic Acidosis, and Stroke-like episodes) syndrome is one of the inherited mitochondrial disorder. We have experienced a 16-year-old girl with headaches and left hemianopsia. Diagnosis of MELAS syndrome with multiple brain parenchymal lesions was confirmed by gene study. The stroke-like lesion of MELAS syndrome showed significant improvement in radiological follow up study. Therefore, MRI findings in MELAS could be interpreted as metabolic cellular dysfunction rather than ischemic vasculopathy.