A case of suspected bacterial meningoencephalitis in a Miniature Pinscher dog

  • Accepted : 2006.12.01
  • Published : 2006.12.30

Abstract

A 4-year-old male Miniature Pinscher was referred because of head tilt, nystagmus, and ataxia. The hemogram revealed a moderate neutrophilic leukocytosis. On magnetic resonance imaging, cerebellar inflammation was detected. And cerebrospinal fluid analysis indicated marked neutrophilic pleocytosis. Based on these results, bacterial meningoencephalitis was suspected. The clinical signs were well controlled by a combination antibiotics therapy of the third generation cephalosporins (cefotaxime and cefixime) and metronidazole. We tentatively diagnosed this case as a bacterial meningoencephalitis because clinical signs were improved after only antibiotics therapy and relapsed when stopped antibiotics administrations, even though the result of bacterial culture on communication of cerebrospinal fluid (CSF) was negative.

Keywords

References

  1. Allan R, Fenwick SG, Clark P, Cave N. Meningitis in a dog caused by Prevotella oralis. J Small Anim Pract 2004, 45, 421-423 https://doi.org/10.1111/j.1748-5827.2004.tb00260.x
  2. Dewey CW. Encephalopathies. In: Dewey CW (ed.). A Practical Guide of to Canine and Feline Neurology, 1st ed. pp. 142-146, Blackwell, Ames, 2003
  3. Gray LD, Fedorko DP. Laboratory diagnosis of bacterial meningitis. Clin Microbiol Rev 1992, 5, 130-145 https://doi.org/10.1128/CMR.5.2.130
  4. Haburjak JJ, Schubert TA. Flavobacterium breve meningitis in a dog. J Am Anim Hosp Assoc 1997, 33, 509-512 https://doi.org/10.5326/15473317-33-6-509
  5. Hudson MD. Bacterial meningitis: A case study and review. J Am Anim Hosp Assoc 1976, 12, 88-91
  6. Irwin PJ, Parry BW. Streptococcal meningoencephalitis in a dog. J Am Anim Hosp Assoc 1999, 35, 417-422 https://doi.org/10.5326/15473317-35-5-417
  7. Meric SM. Corticosteroid therapy for bacterial meningitis in dogs. Cornell Vet 1990, 80, 3-6
  8. Quagliarello V, Scheld WM. Bacterial meningitis: pathogenesis, pathophysiology, and progress. N Engl J Med 1992, 327, 864-872 https://doi.org/10.1056/NEJM199209173271208
  9. Radaelli ST, Platt SR. Bacterial meningoencephalomyelitis in dogs: a retrospective study of 23 cases (1990-1999). J Vet Intern Med 2002, 16, 159-163
  10. Tipold A. Diagnosis of inflammatory and infectious diseases of the central nervous system in dogs: a retrospective study. J Vet Intern Med 1995, 9, 304-314 https://doi.org/10.1111/j.1939-1676.1995.tb01089.x
  11. Tunkel AR, Wispelwey B, Scheld WM. Bacterial meningitis: recent advances in pathophysiology and treatment. Ann Intern Med 1990, 112, 610-623 https://doi.org/10.7326/0003-4819-112-8-610