The Incidence and Risk Factors of Hypertension that Developed in a Male-workers' Cohort for 3 Years

일부 남성근로자의 3년간 고혈압 발생률과 위험요인

  • Seo, Hyun-Ju (Radiation Health Research Institute, Korea Hydro & Nuclear Power CO.,LTD.) ;
  • Kim, Chong-Soon (Radiation Health Research Institute, Korea Hydro & Nuclear Power CO.,LTD.) ;
  • Chang, Yun-Kyun (Radiation Health Research Institute, Korea Hydro & Nuclear Power CO.,LTD.) ;
  • Park, Il-Geun (Radiation Health Research Institute, Korea Hydro & Nuclear Power CO.,LTD.) ;
  • Kim, Soo-Geun (Radiation Health Research Institute, Korea Hydro & Nuclear Power CO.,LTD.)
  • 서현주 (한국수력원자력 (주) 방사선보건연구원) ;
  • 김종순 (한국수력원자력 (주) 방사선보건연구원) ;
  • 장윤균 (한국수력원자력 (주) 방사선보건연구원) ;
  • 박일근 (한국수력원자력 (주) 방사선보건연구원) ;
  • 김수근 (한국수력원자력 (주) 방사선보건연구원)
  • Published : 2006.05.01

Abstract

Objectives: Cardiovascular disease is one of the main causes of death and morbidity in Korea. In this study, the prevalence and incidence of developing hypertension in a male-workers' cohort were investigated during 3-years follow-up with a view to find the risk factors that affected the development of hypertension. Methods: Among the 5,374 people who participated in a routine health check up, 3,852 people with normal blood pressure and who had no history of hypertension were prospectively followed up for 3 years. The classification of hypertension was based on the JNC7 report (the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure). Life style factors and underlying diseases that were related to the risk factors of hypertension were collected by using a self-report questionnaires via the internet. Results: The prevalence of hypertension was 28.3% (1,520/5,374) at the first screening (2001). It was found that the incidence in 2004 of hypertension for the follow-up subjects (3,711) who had normal blood pressure in 2001 was 7.6 per 100 person-year. Multiple logistic regression analysis of the variables related to the risk factors of hypertension was carried out. The relative risks were 1.037 (95% CI=1.022-1.053) as the age increased 1 year and 1.039 (95% CI=1.023-1.055) as the body mass index increased $1kg/m^2$. The relative risk for the prehypertensive group was 2.501 (95% CI=1.986-3.149) compared to the normotensive group. These results showed that age, body mass index and the baseline blood pressure were significantly related to the incidence of hypertension. Conclusions: The incidence of hypertension was 7.6 per 100 person-year during follow-up. It was concluded that the risk factors for developing hypertension in the short-term were age, BMI, and prehypertension; Especially, this showed that it is necessary for prehypertensives to manage their body weight and blood pressure to prevent hypertension in middle-age by modifying their life style.

Keywords

References

  1. Korea National Statistical Office; 2005. Important Death Cause in Korea; 2004
  2. Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global burden of disease study. Lancet 1997; 349(9063): 1436-1442 https://doi.org/10.1016/S0140-6736(96)07495-8
  3. Lindgren A, Pukkala E, Nissinen A, Kataja V, Notkola IL, Tuomilehto J. Cancer incidence in hypertensive patients in North Karelia, Finland. Hypertension 2001; 37(5): 1251-1255 https://doi.org/10.1161/01.HYP.37.5.1251
  4. Lee DH, Cho EL, Kang DL. Blood Pressure in Korean-Korea National Health and Nutrition Survey 2001. 56th -Autumn Conference of Scholarship Collection. The Korean Society for Preventive Medicine; 2004 (Korean)
  5. Jung KW, Uhm SH, Choi SK, Kim JH, Lee JT, Jeon JH, Lee CH, Bae KT. A study on prevalence rates and close examinations of hypertension workers among white-collar workers in Seoul. Inje Med J 1997; 18(1): 113-125 (Korean)
  6. Jo I, Ahn Y, Lee J, Shin KR, Lee HK, Shin C. Prevalence, awareness, treatment, control and risk factors of hypertension in Korea: The Ansan study. J Hypertens 2001; 19(9): 1523-1532 https://doi.org/10.1097/00004872-200109000-00002
  7. Kim HC, Suh I, Jee SH, Lee KH, Kim CS, Nam JM. Twelve-year incidence of hypertension and its risk factors in a lean population: The Kangwha study. Korean J Prev Med 1999; 32(4): 435-442 (Korean)
  8. Oh HS, Chun BY, Kam S, Yeh MH, Kang YS, Kim GY, Lee YS, Park KS, Son JH, Lee SW, Ahn MY. The risk factors for the development of hypertension in a rural area -An 1 year prospective cohort study-. Korean J Med 2000; 33(2): 199-207 (Korean)
  9. Chun BY, Kam S, Oh HS, Lee SW, Woo GH, Ahn MY. Incidence of hypertension in a cohort of an adult population. Korean J Prev Med 2002; 35(2): 141-146 (Korean)
  10. Kam S, Yeh MH, Lee SK, Chun BY. A casecontrol study for risk factor related to hypertension. Korean J Prev Med 1991; 24(2): 221-231 (Korean)
  11. Masahiko Tozawa, Saari Oshiro, Chiho Iseki, Shogo Sesoko, Yasushi Higashiuesato, Takeshi Tana, Yoshiharu Ikemiya, Kunitoshi Iseki, Koshiro Fukiyama. Multiple risk factor clustering of hypertension in a screened cohort. J Hypertens 2000; 18(10): 1375-1385
  12. Lee KY, Cho BM. The association between body weight and hypertension according to smoking status in male workers. J Korean Acad Fam Med 2002; 23(5): 613-619 (Korean)
  13. Borghi C, Veronesi M, Bacchelli S, Esposti DD, Cosentino E, Ambrosioni E. Serum cholesterol levels, blood pressure response to stress and incidence of stable hypertension in young subjects with high normal blood pressure. J Hypertens 2004; 22(2): 265-272 https://doi.org/10.1097/00004872-200402000-00009
  14. Jiang H, Michael JK, Lawrence JA, Jeanne C, Paul KW. Seven-year incidence of hypertension in cohort of middle-aged African Americans and Whites. Hypertension 1998; 31(5): 1130-1135 https://doi.org/10.1161/01.HYP.31.5.1130
  15. U.S. Department of Health and Human Services. JNC 7 Express: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Available from: URI :http://www.nh1bi.nih.gov/guidelines/hypertension/express.pdf
  16. Lee DH, Ha MH, Kim JR, David R. Jacobs, Jr. Effects of smoking cessation on changes in blood pressure and incidence of hypertension : A 4-year follow-up study. Hypertension 2001; 37(2): 194-198 https://doi.org/10.1161/01.HYP.37.2.194
  17. Lee GE, Kim YS. The prevalence of prehypertension and hypertension among adult attendees of health promotion-obesity Expo in Seoul. Korean J Health Promot Dis Prev 2004; 4(2): 82-89 (Korean)
  18. Bae JM, Ahn YO. A nested case-control study on the high normal blood pressure as a risk factor of hypertension in Korean middle-aged men. Korean J Prev Med 1999; 32(4): 513-525 (Korean)
  19. Masaru Miyao, Masashi Furuta, Hisataka Sakakibara, Taka-aki Kondo, Shin' ya Ishihara, Katsumi Yamanaka, Shin' ya Yamada. Analysis of factors related to hypertension in Japanese middle-aged male workers. J Hum Hypertens 1992; 6(3): 193-197
  20. Vasan RS, Larson MG, Leip EP, Kannel WB, Levy D. Assessment of frequency of progression of hypertension in nonhypertensive participants in the Framingham Heart Study: A cohort study. Lancet 2001; 358(9294): 1682-1686 https://doi.org/10.1016/S0140-6736(01)06710-1
  21. Okubo Y, Suwazono Y, Kobayashi E, Nogawa K. Alcohol consumption and blood pressure change: 5-year follow-up study of the association in normotensive workers. J Hum Hypertens 2001; 15(6): 367-372 https://doi.org/10.1038/sj.jhh.1001191
  22. Xue X, Jiang H, Maria GF, Lorraine GO, Oaitse IM, Paul KW. Effects of alcohol reduction on blood pressure - A meta-analysis of randomized controlled trials -. Hypertension 2001; 38(5): 1112-1117 https://doi.org/10.1161/hy1101.093424