Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Trilostane Treatment in a Dog with Pituitary-Dependent Hyperadrenocorticism

뇌하수체 의존성 부신피질기능항진증 이환견의 Trilostane 치료 1례

  • Lim Young-Hwan (College of Veterinary Medicine, Chungnam National University) ;
  • Lee Jung-Youn (Obihiro University of Agriculture and Veterinary Medicine) ;
  • Cho Sung-Nam (College of Veterinary Medicine, Chungnam National University) ;
  • Park Seong-Jun (College of Veterinary Medicine, Chungnam National University) ;
  • Choi Ho-Jung (College of Veterinary Medicine, Chungnam National University) ;
  • Lee Young-Won (College of Veterinary Medicine, Chungnam National University) ;
  • Song Kun-Ho (College of Veterinary Medicine, Chungnam National University)
  • Published : 2006.06.01
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Abstract

A 7-year-old, spayed female, Yorkshire terrier dog with polyuria/polydipsia (PU/PD), interdigital edema, pruritus and abdominal enlargement was referred to the Veterinary Medical Teaching Hospital of the present university. Pituitary-dependent hyperadrenocortisim (PDH) was diagnosed by clinical signs, physical examination, laboratory examination (complete blood count, serum chemistry, urinalysis, ACTH stimulation test and high dose dexamethasone suppression test) and diagnostic imaging (radiography, ultrasonography and computed tomography). Clinical signs were improved after trilostane treatment, and maintenance therapy with trilostane still continued after successful induction therapy. Trilostane can be used as an alternative to mitotane therapy in hyperadrenocortisim in dogs.

Keywords

References

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