한국자기공명학회논문지 (Journal of the Korean Magnetic Resonance Society)

한국자기공명학회 (Korean Magnetic Resonance Society)
권호 표지

Evaluation of Hydration Effect on Human Skin by $^1H$ MRS at 14.1T

  • Choi Chi-Bong (Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea) ;
  • Hong Sung-Tak (Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea) ;
  • Choe Bo-Young (Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea) ;
  • Woo Dong-Chul (Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea) ;
  • Yoon Seong-Ik (Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea) ;
  • Cho Ji-Hyun (Korea Basic Science Institute) ;
  • Lee Chul-Hyun (Korea Basic Science Institute) ;
  • Cheong Chae-Joon (Korea Basic Science Institute) ;
  • Park Sang-Yong (Research Institute of Skin Imaging and Department of Dermatology, School of Medicine, Korea University) ;
  • Oh Chil-Hwan (Research Institute of Skin Imaging and Department of Dermatology, School of Medicine, Korea University)
  • 발행 : 2006.06.01
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초록

Purpose: We achieved high resolution MR imaging and spectra of human skin in vitro with using a 14.1 T MRI/MRS system, and evaluated the hydration effect of various cosmetic products by measuring the skin's. moisture concentration. Materials and Methods: We used the Bruker 14.1 T MRI/MRS system with a vertical standard bore that was equipped with a DMX spectrometer gradient system (200 G/cm at a maximum 40 A), RF resonators (2, 5 and 10 mm) and Para Vision software. Spin echo and fast spin echo pulse sequences were employed for obtaining the high resolution MR images. The 3D-localized point resolved spectroscopy (PRESS) method was used to acquire the MR spectra. Results: The high resolution MR images and spectra of human skin in vitro were successfully obtained on a 14.1 T system. The water concentration of human skin after applying a moisturizer was higher than that before applying a moisturizer. Conclusions: The present study demonstrated that the high-resolution MR images and spectra of human skin from a high field NMR instrument could be applicable to evaluating the hydration state of the stratum corneum.

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