The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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The Effects of YUKWOOLTANG(六鬱湯) on the Hyperthyroidism of Rats

육울탕이 백서의 갑상선기능항진증에 미치는 영향

  • Choi, Hoon-Seob (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Cheol-Jung (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Cho, Chung-Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 최훈섭 (대전대학교 한의과대학 신계내과학 교실) ;
  • 김철중 (대전대학교 한의과대학 신계내과학 교실) ;
  • 조충식 (대전대학교 한의과대학 신계내과학 교실)
  • Published : 2006.12.30
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Abstract

Objectives : The aim was to study experimentally the effects of YUKWOOLTANG(li${\`{u}}$y${\`{u}}$-t${\={a}}$ng; YWT) induced by sodium levothyroxine. Methods : Spargue-Dawley rats were separated into four groups. Except normal group, the other three groups were treated with sodium levothyroxine $32{\mu}g$/200g for 5 days. Among the three groups, two except one(as control group) were treated YWT extract separately(sample A:75mg/200 g, sample B: 150mg/200 g ). T3-uptake, T3, T4, r-TSH, total cholesterol, total protein change in the serum of rats were measured after medication of solid extract of YWT. Results : As a result of this study, in the serum T3-uptake content, sample A showed significant decrease in comparison with control group, but sample B group did not show significant decrease. 2. In the serum T3 content, sample B showed significant decrease in comparison with control group. In the serum T4 content, YWT showed significant decrease in comparison with control group. The serum r-TSH was shown with valuable increase in sample B of YWT. The serum total cholesterol was not shown with valuable increase in YWT. The serum total protein was shown with valuable increase in YWT. Conclusion : These results suggest that YWT is effective to cure Hyperthyroidism.

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