The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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The Effects of KABHANGBANG(KHB) on the Hyperthyroidism of Rats

갑항방이 백서의 갑상선기능항진증에 미치는 영향

  • Kim, Min-Seok (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Cheol-Jung (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Cho, Chung-Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 김민석 (대전대학교 한의과대학 신계내과학 교실) ;
  • 김철중 (대전대학교 한의과대학 신계내과학 교실) ;
  • 조충식 (대전대학교 한의과대학 신계내과학 교실)
  • Published : 2006.12.30
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Abstract

Objectives : The aim was to study experimentally the effects of KABHANG-BANG(갑항방) on the hyperthyroidism of rats induced by sodium levothyroxine. Methods : Spargue-Dawley rats were separated into four groups. Except normal group, the other three groups were treated with sodium levothyroxine $32{\mu}g$/200g/days for 5 days by oral administration. Among the three groups, two except one(as control) were treated KHB extract 225mg/200g/days(sample A), 450mg/200g/days(sample B) for 3 days separately. T3-uptake, T3, T4, r-TSH, total cholesterol, total protein change in the Serum of rats were measured after medication of solid extract of KHB. Results : As a result of this study, in the serum T3 and T4 level were decreased in sample A and B compared to controls. The serum r-TSH, total cholesterol and total protein were increase in sample A and B compared to controls. In the serum T3-uptake content, Smple B showed significant decrease in comparison with control group, but Sample A did not show significant decrease. Conclusion : According to the above results, it is suggested that KHB is effective to cure hyperthyroidism.

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