The Effects of Treadmill Exercise on the Recovery of Functional Capacity in Spinal Cord Injured Rats

트레드밀 운동이 척수손상 백서의 운동기능 회복에 미치는 효과

  • Chun, Jin-Sung (A Physical Therapy Doctor, Graduate School of Dongshin University) ;
  • Kim, Tae-Youl (College of Health & Wealfare, Dongshin University) ;
  • Nam, Ki-Won (College of Health & Wealfare, Dongshin University) ;
  • Kim, Young-Eok (College of Health & Wealfare, Dongshin University) ;
  • Oh, Myung-Hwa (College of Health & Wealfare, Dongshin University) ;
  • Kim, Kyoung-Yoon (College of Health & Wealfare, Dongshin University) ;
  • Kim, Eun-Jung (A Physical Therapy Doctor, Graduate School of Dongshin University) ;
  • Lee, Jae-Choon (Department of Physical Therapy, Kunjang College) ;
  • Jang, Mee-Kyung (Department of Diet & Health Management, Dongkang College) ;
  • Choi, Hyun-Seok (Department of Occupational Therapy, Sunghwa College) ;
  • Heo, Myung (A Physical Therapy Doctor, Graduate School of Dongshin University) ;
  • Kim, Gye-Yeop (College of Health & Wealfare, Dongshin University)
  • 천진성 (동신대학교 대학원 물리치료) ;
  • 김태열 (동신대학교 보건복지대학 물리치료학과) ;
  • 남기원 (동신대학교 보건복지대학 물리치료학과) ;
  • 김용억 (동신대학교 보건복지대학 물리치료학과) ;
  • 오명화 (동신대학교 보건복지대학 물리치료학과) ;
  • 김경윤 (동신대학교 보건복지대학 물리치료학과) ;
  • 김은정 (동신대학교 대학원 물리치료) ;
  • 이재춘 (군장대학 물리치료과) ;
  • 장미경 (동강대학 다이어트 건강관리과) ;
  • 최현석 (성화대학 작업치료과) ;
  • 허명 (동신대학교 대학원 물리치료) ;
  • 김계엽 (동신대학교 보건복지대학 물리치료학과)
  • Published : 2007.08.25

Abstract

Purpose: This study was designed to investigate the effects of treadmill exercise on functional recovery after rat with experimental SCI. Methods: SCI was induced by the NYU-spinal cord impactor(NYU, USA) dropped a weight of 10 gm after laminectomy. Experimental groups were divided into the Group I (normal), Group II (control) and Group III(treadmill exercise). After 2 days of the operation, 24 rats(group II, III) were trained to walk on treadmill for 21 days twice/day, 15 min/session. After operation, rats were tested at modified Tarlov scale at 1, 2, 3, 4 days with divided into 2 groups, and Motor behavior test(BBB locomotor rating scale, Grid walking test, Narrow beam crossing test, Modified inclined plane test) was examined at 1, 3, 7, 14 and 21 days. Histopathological study were performed at 1. 3, 7, 14 and 21 days by H&E, Luxol Fast Blue staining were same times. Results: After SCI an improvement of motor behavior was shown group II, III. The motor behavior test of group Ill showed considerable improvement until 14 days. Conclusion: These results suggest that treadmill exercise treatment can playa role in facilitating recovery of locomotion following spinal cord injury.

Keywords