Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Analysis on the Blood F1ow, Pressure and Pulsatility of a Dual Pulsatile Extracorporeal Life Support

이중 박동형 생명구조장치의 혈류, 혈압, 박동성의 분석

  • Choi, Seong-Wook (Program of Mechanics and Biomedical Engineering. College of Engineering, Kangwon National University) ;
  • Min, Byoung-Goo (Department of Biomedical Engineering, College of Medicine, Seoul National University)
  • 최성욱 (강원대학교 공과대학 기계메카트로닉스 공학부 기계의용공학) ;
  • 민병구 (서울대학교 의과대학 의용생체공학교실)
  • Published : 2007.10.31
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Abstract

Previous trials for development of a pulsatile-Extracorporeal Life Support had some defects such as insufficient blood flow, high pressure at its membrane oxygenator and the high risk of blood cell damage. To solve those problems of previous pulsatile-ECLSs, we suggest dual pulsatile blood pump structure for the new pulsatile-ECLS. Two pulsatile pumps areconnected in a parallel manner and this new structure raises the inflow capacity and efficiency and it decreases the high blood pressure at membrane oxygenator. In in-vitro experiments, The Energy Equivalent Pressure Increment(EEP inc.) was 10%, and it showed that its pulsatilty was $5{\sim}10$ times higher than other commercial ECLS In in-vivo experiments, we had applied a new pulsatile-ECLS to 30 Kg pigs and a new pulsatile-ECLS couldsupport high blood flow and pulsatility above 2 L/min, 10% EEP inc.

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References

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