Antipruritic Effect of Black Colored Rice

  • Published : 2007.12.31

Abstract

Antiscratching behavioral effects of the water extract of two black colored rice (BCR) varieties [Oryza sativa L. cv. Heugjinjubyeo (HJ) and Josaengheugchalbyeo (JH)], major pigment of which is cyanindin 3-glucoside, were investigated. Orally administered BCRs' extracts exhibited potent inhibitory activity against scratching behaviors which were induced by compound 48/80 and histamine. The inhibitory effect of Josaengheugchalbyeo in vivo and in vitro were more potent than those of Heugjinjubyeo. These finding suggest that black colored rice, especially Josaengheugchalbyeo, may inhibit scratching behaviors and anaphylaxis reaction by stabilizing membrane.

Keywords

References

  1. Andoh, T., Katsube, N., Maruyama, M., and Kuraishi, Y., Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice. J. Invest. Dermatol. 117, 1621-1626 (2001) https://doi.org/10.1046/j.0022-202x.2001.01585.x
  2. Azuma, H., Banno, K., and Yoshimura, T., Pharmacological properties of N-(3',4'-dimethoxycinnamoyl) anthranilic acid (N-5'), a new antiatopic agent. Br. J. Pharmacol. 58, 483-488 (1976) https://doi.org/10.1111/j.1476-5381.1976.tb08614.x
  3. Benyon, R.C., Robinson, C., and Church, M.K., Differential release of histamine and eicosanoids from human skin mast cells activated by IgE-dependent and non-immunological stimuli. Br. J. Pharmacol. 97, 898-904 (1989) https://doi.org/10.1111/j.1476-5381.1989.tb12030.x
  4. Chand, N., Pillar, J., Diamantis, W., Perhach, J.L., Jr., and Sofia, R.D., Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: implications for its mode of action. Eur. J. Pharmacol. 96, 227-233 (1983) https://doi.org/10.1016/0014-2999(83)90311-4
  5. Choo, M.K., Park, E.K., Han, M.J., and Kim, D.H., Antiallergic activity of ginseng and its ginsenosides. Planta Med. 69, 518-522 (2003) https://doi.org/10.1055/s-2003-40653
  6. Cox, J.S., Disodium cromoglycate (FPL 670) ('Intal'): a specific inhibitor of reaginic antibody-antigen mechanisms. Nature 216, 1328-1329 (1967) https://doi.org/10.1038/2161328a0
  7. FAO, International year of rice 2004 - rice and human nutrition. vol. 2006. Food and Agriculture Organization of the United Nations, 2004
  8. Friedman, E.S., LaNatra, N., and Stiller, M.J., NSAIDs in dermatologic therapy: review and preview. J. Cutan. Med. Surg. 6, 449-459 (2002) https://doi.org/10.1007/s10227-001-0137-3
  9. Hagermark, O., Itch mediators. Semin. Dermatol. 14, 271-276 (1995)
  10. Han, S.J., Ryu, S.N., and Kang, S.S., A new 2-arylbenzofuran with antioxidant activity from the black colored rice (Oryza sativa L.) bran. Chem. Pharm. Bull. (Tokyo) 52, 1365-1366 (2004) https://doi.org/10.1248/cpb.52.1365
  11. Hu, C., Zawistowski, J., Ling, W., and Kitts, D.D., Black rice (Oryza sativa L. indica) pigmented fraction suppresses both reactive oxygen species and nitric oxide in chemical and biological model systems. J. Agric. Food Chem .51, 5271-5277 (2003) https://doi.org/10.1021/jf034466n
  12. Inagaki, N., Igeta, K., Kim, J.F., Nagao, M., Shiraishi, N., Nakamura, N., and Nagai, H., Involvement of unique mechanisms in the induction of scratching behavior in BALB/c mice by compound 48/80. Eur. J. Pharmacol. 448, 175-183 (2002) https://doi.org/10.1016/S0014-2999(02)01933-7
  13. Inagaki, N., Nagao, M., Nakamura, N., Kawasaki, H., Igeta, K., Musoh, K., and Nagai, H., Evaluation of anti-scratch properties of oxatomide and epinastine in mice. Eur. J. Pharmacol. 400, 73-79 (2000a) https://doi.org/10.1016/S0014-2999(00)00349-6
  14. Inagaki, N., Nakamura, N., Nagao, M., Kawasaki, H., and Nagai, H., Inhibition of passive cutaneous anaphylaxis-associated scratching behavior by mu-opioid receptor antagonists in ICR mice. Int. Arch. Allergy Immunol. 123, 365-368 (2000b) https://doi.org/10.1159/000053650
  15. Kim, H.M., Kang, C.S., Lee, E.H., and Shin, T.Y., The evaluation of the antianaphylactic effect of Oryza sativa L. subsp. hsien Ting in rats. Pharmacol. Res. 40, 31-36 (1999a) https://doi.org/10.1006/phrs.1998.0386
  16. Kim, H.M., Yi, D.K., and Shin, H.Y., The evaluation of antianaphylactic effect of Oryza sativa L. in rats. Am, J, Chin, Med, 27, 63-71 (1999b) https://doi.org/10.1142/S0192415X99000094
  17. Kuraishi, Y., Nagasawa, T., Hayashi, K., and Satoh, M., Scratching behavior induced by pruritogenic but not algesiogenic agents in mice. Eur. J. Pharmacol. 275, 229-233 (1995) https://doi.org/10.1016/0014-2999(94)00780-B
  18. Lerner, E.A., Chemical mediator of itching. in: Berhard, J. (Ed.), Itch Mechanisms and Management of Prutitus. McGraw-Hill, New York, pp. 23-25, 1994
  19. Ohmori, H., Hikida, M., and Takai, T., Prostaglandin E2 as a selective stimulator of antigen-specific IgE response in murine lymphocytes. Eur. J. Immunol. 20, 2499-2503 (1990) https://doi.org/10.1002/eji.1830201121
  20. Oki, T., Masuda, M., Kobayashi, M., Nishiba, Y., Furuta, S., Suda, I., and Sato, T., Polymeric procyanidins as radical-scavenging components in red-hulled rice. J. Agric. Food Chem. 50, 7524-7529 (2002) https://doi.org/10.1021/jf025841z
  21. Raid, D.S., Pruritis of chronic cholestasis. Q. J. Med. 88, 603-607 (1955)
  22. Rukwied, R., Lischetzki, G., McGlone, F., Heyer, G., and Schmelz, M., Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients: a dermal microdialysis study. Br. J. Dermatol. 142, 1114-1120 (2000) https://doi.org/10.1046/j.1365-2133.2000.03535.x
  23. Ryu, S.N., Park, S.Z., Kang, S.S., and Han, S.J., Determination of C3G content in blackish purple rice using HPLC and UV-Vis spectrophotometer. Korean J. Crop Sci. 48, 369-371 (2003)
  24. Sakuma, S., Higashi, Y., Sato, N., Sasakawa, T., Sengoku, T., Ohkubo, Y., Amaya, T., and Goto, T., Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system. (Comparison with steroids). Int Immunopharmacol 1: 1219-1226 (2001) https://doi.org/10.1016/S1567-5769(01)00059-5
  25. Schafer-Korting, M., Schmid, M.H., and Korting, H.C., Topical glucocorticoids with improved risk-benefit ratio. Rationale of a new concept. Drug Saf. 14, 375-385 (1996) https://doi.org/10.2165/00002018-199614060-00003
  26. Schmelz, M., Schmidt, R., Bickel, A., Handwerker, H.O., and Torebjork, H.E., Specific C-receptors for itch in human skin. J. Neurosci. 17, 8003-8008 (1997) https://doi.org/10.1523/JNEUROSCI.17-20-08003.1997
  27. Simons, F.E., The antiallergic effects of antihistamines (H1-receptor antagonists). J. Allergy Clin. Immunol. 90, 705-715 (1992) https://doi.org/10.1016/0091-6749(92)90156-V
  28. Stevens, R.L. and Austen, K.F., Recent advances in the cellular and molecular biology of mast cells. Immunol. Today 10, 381-386 (1989) https://doi.org/10.1016/0167-5699(89)90272-7
  29. Suba, V., Murugesan, T., Kumaravelrajan, R., Mandal, S.C., and Saha, B.P., Antiinflammatory, analgesic and antiperoxidative efficacy of Barleria lupulina Lindl. extract. Phytother. Res. 19, 695-699 (2005) https://doi.org/10.1002/ptr.1734
  30. Sugimoto, Y., Umakoshi, K., Nojiri, N., and Kamei, C., Effects of histamine H1 receptor antagonists on compound 48/80-induced scratching behavior in mice. Eur. J. Pharmacol. 351, 1-5 (1998) https://doi.org/10.1016/S0014-2999(98)00288-X