Extraskeletal Osteosarcoma of the Mammary Gland in a Dog

개의 유선에 발생한 골격외 골육종 1예

  • Hong, Ji-Hyun (Clinical pathology, College of Veterinary Medicine, Seoul National University) ;
  • Bae, Bo-Kyung (Clinical pathology, College of Veterinary Medicine, Seoul National University) ;
  • Go, Young-Hwan (Clinical pathology, College of Veterinary Medicine, Seoul National University) ;
  • You, Mi-Hyeon (Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Choi, Eul-Soo (Clinical pathology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Dae-Yong (Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Chang-Woo (Clinical pathology, College of Veterinary Medicine, Seoul National University)
  • 홍지현 (서울대학교 수의과대학 임상병리학교실) ;
  • 배보경 (서울대학교 수의과대학 임상병리학교실) ;
  • 고영환 (서울대학교 수의과대학 임상병리학교실) ;
  • 유미현 (서울대학교 수의과대학 병리학교실) ;
  • 최을수 (서울대학교 수의과대학 임상병리학교실) ;
  • 김대용 (서울대학교 수의과대학 병리학교실) ;
  • 이창우 (서울대학교 수의과대학 임상병리학교실)
  • Published : 2007.12.31

Abstract

A 16-year-old female Poodle with multiple mammary masses was referred to the Veterinary Medical Teaching Hospital of Seoul National University. Radiographic finding indicated a round mass of soft tissue density at the ventral portion of the 4th-7th sternum, which was 7 cm in diameter and presented multiple mineralization within the mass. Cytologically, aspirate of the mammary mass was moderately cellular and revealed well-differentiated osteoblasts with moderately basophilic cytoplasm, various sized and eccentrically placed nuclei and distinct nucleoli. Osteoblasts interspersed with osteoid-suspected pink-staining intercellular matrix. Some cells displayed malignant features such as macronuclei, macronucleoli, binucleation, abnormal mitotic figures, anisocytosis and anisokaryosis. On which the mass was diagnosed as osteosarcoma. Histopathologic examinations of the mass were compatible with a diagnosis of osteosarcoma. The patient was treated with surgery alone. The patient died 45 days later from surgery.

Keywords

References

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