Anti-aging Effects Saccharomyces Fermented Modified Kyungohkgo Extract on Skin

경옥고(瓊玉膏) 가미방(加味方) 효모(酵母) 발효물(醱酵物)이 피부(皮膚) 노화(老化)에 미치는 영향(影響)

  • Choi, Jae-Hwan (Oriental Herb Cosmeceutical R&D Center, LG Household & Healthcare Ltd./Research Park) ;
  • Kim, Hyoung-Man (Cosmetics R&D Center, LG Household & Healthcare Ltd./Research Park) ;
  • Song, Young-Sook (Cosmetics R&D Center, LG Household & Healthcare Ltd./Research Park) ;
  • Park, Sun-Gyoo (Oriental Herb Cosmeceutical R&D Center, LG Household & Healthcare Ltd./Research Park) ;
  • Kim, Jin-Jun (Cosmetics R&D Center, LG Household & Healthcare Ltd./Research Park) ;
  • Lee, Cheon-Koo (Cosmetics R&D Center, LG Household & Healthcare Ltd./Research Park)
  • 최재환 ((주)LG생활건강 기술연구원 후 한방피부과학연구소) ;
  • 김형만 ((주)LG생활건강 기술연구원 화장품연구소) ;
  • 송영숙 ((주)LG생활건강 기술연구원 화장품연구소) ;
  • 박선규 ((주)LG생활건강 기술연구원 후 한방피부과학연구소) ;
  • 김진준 ((주)LG생활건강 기술연구원 화장품연구소) ;
  • 이천구 ((주)LG생활건강 기술연구원 화장품연구소)
  • Published : 2007.12.31

Abstract

Objectives : We investigated the anti-aging effects on skin with Saccharomyces fermented modified Kyungohkgo extract (SFKE). Methods : Fermented modified Kyungohkgo extracts by 14 different kinds of microorganism were prepared and most effective Saccharomyces fermented modified Kyungohkgo extract among these was selected for anti-aging agent. We measured various effects related to skin such as scavenging activity against free radical, cell proliferation, collagen synthesis and toxicity of SFKE were evaluated and compared with modified Kyungohkgo extract (KE). Results : Free-radical scavenging activity and cell proliferating ratio of SFKE were 2 and 8 times higher than those of KE. The SFKE could significantly increase the collagen synthetic ratio compared with KE treated group. SFKE showed no toxicity at all tested concentrations. Conclusions : The results of our study propose that SFKE have good anti-aging effects on skin.

Keywords