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Korean Society for Biochemistry and Molecular Biology (생화학분자생물학회)
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Ghrelin is Present in Teeth

  • Aydin, Suleyman (Department of Biochemistry and Clinical Biochemistry, Firat University, Medical School (Firat Medical Center)) ;
  • Ozercan, I brahim Hanefi (Department of Pathology, Firat University, Medical School (Firat Medical Center)) ;
  • Geckil, Hikmet (Department of Molecular Biology, Inonu University) ;
  • Dagli, Ferda (Department of Pathology, Firat University, Medical School (Firat Medical Center)) ;
  • Aydin, Suna (Department of Cardiovascular Surgery, Firat University, Medical School (Firat Medical Center)) ;
  • Kumru, Sinem (Doctors Business Center, Tooth Clinic) ;
  • Kilic, Nermin (Department of Biochemistry and Clinical Biochemistry, Firat University, Medical School (Firat Medical Center)) ;
  • Sahin, I brahim (Biochemistry section-Biology, Firat University) ;
  • Ozercan, Mehmet Resat (Department of Pathology, Firat University, Medical School (Firat Medical Center))
  • Published : 2007.05.31
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Abstract

Ghrelin belongs to the family of a gut-brain hormone that promotes food intake and controls energy balance. Recently, it has also been shown to regulate bone formation directly. Dental tissue shares several functional, developmental and anatomical similarities with bone, and in the present study we have investigated the presence of ghrelin in 44 human teeth using immunocytochemistry and radioimmunoassay. Both methods showed that the hormone is present in canines and molars, mainly in the odontoblasts but also in the pulp. Ghrelin could potentially play interesting physiological roles in teeth.

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References

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