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Bone Healing Effect of a Magnet in Sprague Dawley Rats

Sprague Dawley 랫트에서 자장이 골 창상 치유에 미치는 영향

  • Published : 2007.04.30

Abstract

The present study was carried out to examine the bone healing effect of a magnet as the feasibility test for clinical application. The surgical technique of tibia puncture was performed with male Sprague Dawley rats for investigating radiological and histological findings. The treated group was attached the magnet, and control group was attached the placebo magnet for 4, 6, and 8 weeks respectively. The rats were taken a radiograph for examining radiological findings on 2-weekly interval for 8 weeks. Also, the rats were partly euthanized for investigating histological findings on 2-weekly interval from 4 week to 8 week. In the magnet treated rats, the healing process of bone trauma was positively stimulated to compare with control rats.

Keywords

References

  1. 김재원 : 자석 치료, 한국의 침구 100, 한국의 침구사, 87-92, 1996
  2. 김남섭 : 자석 치료법과 각종 치료 처방, 한국의 침구 15, 한국의 침구사, 24-33, 1989
  3. 金永勳, 申佶求, 金在誠, 裵元植 : 國譯 增補 東醫寶鑑, 南山堂, 283, 1966
  4. 申佶求 : 申氏本草學 各論, 壽文社, 147-148, 1973
  5. 지형준, 이상인 : 대한약전외 한약(생약) 규격집 주해서, 한국메디칼인덱스사, 309, 1988
  6. 김준한, 이기남, 박재숙, 서명효 : 족부 염좌에 대한 자석 치료의 임상 예. 대한기공의학회지, 4(2), 53-62, 2000
  7. 장충현 : 자석을 이용한 귓볼 비후성 반흔의 치료. 대한성형외과학회지, 30(4), 520-522, 2003
  8. 탁상현, 김현, 김록호 : 국내 거주환경에서의 전자기장 노출평가를 위한 Wire code의 타당성에 관한 연구. 한국환경위생학회지, 26(3), 55-60, 2000
  9. 김윤신, 현연주, 최성호, 노영만, 홍승철 : 고압 송전선로 주변에 위치한 초등학교 학생들의 극저주파 자기장 노출량 예측 모델에 관한 연구. 한국환경보건학회지, 32(5), 506-514, 2006
  10. 조용성, 김윤신, 이종태, 홍승철, 장성기 : 송전선로 주변과 비주변 초등학생을 대상으로 극저주파 자기장 노출과 뇨중 멜라토닌 분비량간의 상관성 연구. 한국환경보건학회지, 30(3), 191-206, 2004
  11. 이은지 : 자석 치료를 이용한 R.A.환자17예에 대한 임상적 고찰. 대전대학교 부속 한방 병원 惠和醫學, 6(1), 15-31, 1997
  12. 김희수, 권혁근, 김미연, 박영민, 김형옥, 안성열 : 외과적 절제와 자석 압박을 이용한 귓볼 켈로이드의 치료. 대한피부과학회지, 42(2s), 106-107, 2004
  13. Cartmell, S. H., Dobson, J. and Verschueren, S. B. : Development of magnetic particle techniques for long-term culture of bone cells with intermittent mechanical activation. Trans Nanobioscience, Jun., 1(2), 92-97, 2002 https://doi.org/10.1109/TNB.2002.806945
  14. Kirker-Head, C. A. : Recombinant bone morphogenetic proteins: Novel substances for enhancing bone healing. Veterinary Surgery, 24, 408-419, 1995 https://doi.org/10.1111/j.1532-950X.1995.tb01352.x
  15. Orgill, D. and Demling, R. H. : Current concepts and approaches to wound healing. Critical Care Medicine, 16(9), 899-908, 1988 https://doi.org/10.1097/00003246-198809000-00016
  16. Pasaoglu, A., Selcuklu, A., Kandemir, B. and Pasaoglu, H. : Experimental study on osteoplatic cranioplasty using fresh autogenous bone: Comparison of methods and investigation of the effect of L-dopa upon bone healing. Annals of Plastic Surgery, s(5), 418-422, 1988
  17. Pritchett, J. W. : L-dopa in the treatment of nonunited fractures. Clinical Orthopedic and Related Research, 55, 293-300, 1990
  18. 李尙仁, 安德均, 辛民敎 : 漢藥臨床應用, 成輔社, 458-459, 1982
  19. 中華人民共和國厚生部藥典委員會 : 中華人民共和國藥典, 人民厚生出版社, 325, 1985
  20. Dormer, K. J., Richard, G., McGee, M., Hough, J. V. and Shew, R. L. : An implantable hearing device: osseointegration of a titanium-magnet temporal bone stimulator. American Journal of Otology, 7(6), 399-408, 1986 https://doi.org/10.1016/S0196-0709(86)80014-X
  21. Walmsley, A. D., Brady, C. L., Smith, P. L. and Frame, J. W. : Magnet retained overdentures using the Astra dental implant system. British Dental Journal, 174(11), 399-404, 1993 https://doi.org/10.1038/sj.bdj.4808185
  22. Panko, S. V., Antipov IuG., Semenido IuN., Sosnovskaia O. Iu., Golovanova, T. A. and Sanin, A. V. : Suppression of graft versus host reaction by depositing a magnet-controlled adriamycin dosage form in bone marrow allotransplantation in animal experiments. Vestn Ross Akad Med Nauk, 3, 10-15, 2000
  23. Szor, J. K. and Topp, R. : Use of magnet therapy to heal an abdominal wound: A case study. Ostomy Wound Manage, 44(5), 24-29, 1998