Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Effects of High Frequency Electro-acupuncture ($ST_{36}$) on the Adjuvant-induced Arthritis in Rats

족삼리에 시술한 고빈도 전침자극이 류마토이드 관절염 동물모델에 미치는 영향

  • Rho, Boo-Lae (Department of Acupuncture & Moxibustion, College of Orient al Medicine, Se-Myung University) ;
  • Kim, Ee-Hwa (Department of Meridiano1ogy, College of Oriental Medicine, Se-Myung University) ;
  • Lee, Eun-Yong (Department of Acupuncture & Moxibustion, College of Orient al Medicine, Se-Myung University)
  • 노부래 (세명대학교 한의과대학 침구학교실) ;
  • 김이화 (세명대학교 한의과대학 경혈학교실) ;
  • 이은용 (세명대학교 한의과대학 침구학교실)
  • Published : 2007.04.20
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Abstract

Objectives: This study was to investigate the effect of high frequency electro-acupuncture (EA) at $ST_{36}$ acupoint on the Freund's Complete Adjuvant (FCA)-induced arthritis in rats. Methods : Arthritis was induced by intradermal injection of FCA into base of tail. Experimental groups were divided into 4 groups; Normal, Control, $ST_{36}$ and Non-Acupoint (NA). $ST_{36}$ group was treated by 120Hz EA at $ST_{36}$ acupoint. Body weight, paw edema volume and ankle joint thickness were measured after treatment. And we investigated the effects of 120Hz EA via WBC count, segmen neurophil, lymphocyte, PGE2 assay and NADPH-d histochemistry. Results and Conclusions : The mean of body weight and ankle joint thickness of $ST_{36}$ group was increased compared with control group. The mean of paw edema volume, WBC count, segment neutrophil and lymphocyte of were not decreased with control group. The mean of PGE2 concentration ($1,851.00{\pm}160.11$) and NADPH-d positive neurons ($13.12{\pm}1.23$) were changed significantly (p

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