Journal of the Korean Ceramic Society (한국세라믹학회지)

The Korean Ceramic Society (한국세라믹학회)
권호 표지
DOI QR코드

DOI QR Code

Material Design and Analysis of Coronary Artery Stents

관상동맥혈관용 스텐트의 구조해석과 재료설계

  • Park, Joong-Gwun (School of Mechanical and Automotive Engineering, Kookmin University) ;
  • Kang, Tae-Won (School of Mechanical and Automotive Engineering, Kookmin University) ;
  • Lee, Kee-Sung (School of Mechanical and Automotive Engineering, Kookmin University) ;
  • Kim, Tae-Woo (School of Mechanical and Automotive Engineering, Kookmin University)
  • 박중권 (국민대학교 기계자동차공학부) ;
  • 강태원 (국민대학교 기계자동차공학부) ;
  • 이기성 (국민대학교 기계자동차공학부) ;
  • 김태우 (국민대학교 기계자동차공학부)
  • Published : 2007.07.31
Download PDF
⟨ Previous Next ⟩

Abstract

Stent is a tiny structure made with either ceramic coating and/or bare metal. Being approximately $1{\sim}2 mm$ in diameter, it consists of holes, slots, or void space and is designed to cover entire medical lesions. Stent implantation into patients' arteries has been practiced for a little more than a decade in order to widen the blocked artery. The adoption of the stent has significantly improved the efficacy when compared with the previous medical practice by balloon angioplasty alone. Yet better biomedical performance of the stent is being demanded in order to eliminate the still existing problem of artery restenosis, which means the artery becomes narrowed again. Recent literature survey shows researches on ceramic coatings onto the stent surface, or material design to improve the mechanical response of the stent. This study focuses more on the material design and mechanical analysis. The results showed that the void configuration within the stent affects the mechanical response significantly. The rectangular shape was found to yield expansion at a relatively lower pressure than the elliptical slot for a slotted tube stent. The present results, when combined with research on coating at the stent surface, may provide stents with improved bio-medical performance.

Keywords

References

  1. A. D. Callow, 'Cariovascular Disease 2005-the Global Picture,' Vascular Pharmacology, 45 302-07 (2006) https://doi.org/10.1016/j.vph.2006.08.010
  2. C. L. Athanasuleas, G. D. Buckberg, B. S. Allen, F. Beyersdorf, and M. M. Kirsh, 'Sudden Cardiac Death: Directing the Scope of Resuscitation Towards the Heart and Brain,' Resuscitation, 70 44-51 (2006) https://doi.org/10.1016/j.resuscitation.2005.11.017
  3. J. A. Suwaidi and P. B. Berger, 'Do Stents Reduce Mortality Compared with Balloon Angioplasty? A Cirtical Review of all the Evidence,' Am. Heart J., 150 [1] 7-10 (2005) https://doi.org/10.1016/j.ahj.2004.12.018
  4. D. L. Fischman, M. B. Leon, and D. S. Baim, 'A Randomized Comparison of Coronary Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease,' N. Engl. J. Med., 331 496-501 (1994) https://doi.org/10.1056/NEJM199408253310802
  5. R. Hoffmann, G. Mintz, P. K. Haager, T. Bozoglu, E. Grube, M. Gross, C. Beythien, H. Mudra, J. Dahl, and P. Hanrath, 'Relation of Stent Design and Stent Surface Material and to Subsequent in Stent Intimal Hyperplasia in Coronary Arteries Determined by Intravascular Ultrasound,' The American J. of Cardiology, 89 12 (2002)
  6. M. Unverdorben, B. Sippel, R. Degenhardt, K. Sattler, R. Fries, B. Abt, E. Wagner, H. Koeher, G. Daemgen, M. Scholz, H. Ibrahim, K. Tews, B. Hennen, H. Berthold, and C. Vallbracht, 'Comparison of a Silicon Carbide Coated Stent versus a Noncoated Stent in Human Beings: The Tenax versus Nir Stent Study's Long-term Outcome,' Am. Heart J., 145 4 G1-G8 (2003) https://doi.org/10.1016/S0002-8703(03)00267-9
  7. U. Gerckens, L. Buellesfeld, D. Horstkotte, R. Mueller, M. Staberock, G. Sellbach, T. Schmidt, and E. Grube, 'Evaluation of a Tacrolimus-Eluting Coronary Stent with Nanoporous Ceramic Coating in Treatment of Native Coronary Artery Lesions,' Angiography and interventional cardiology, 41 [6] 7A (2003)
  8. C. D. Mario, E. Grube, Y. Nisanci, N. Reifart, A. Colombo, J. Rodermann, R. Muller, S. Ulmman, F. Liistro, M. Montorfano, and E. Alt, 'MOONLIGHT: a Controlled Registry of an Iridium Oxide coated Stent with Angiographic Followup,' Int. J. Cardiology, 95 329-31 (2004) https://doi.org/10.1016/j.ijcard.2003.10.007
  9. S. Windecker, R. Simon, M. Lins, V. Klauss, F. R. Eberli, M. Roffi, G. Pedrazzini, T. Moccetti, P. Wenaweser, M. Togni, D. Tuller, R. Zbinden, C. Seiler, J. Mehilli, A. Kastrati, B. Meier, and O. M. Hess, 'Randomized Comparison of a Titanium-Nitride-Oxide- coated Stent with a Stainless steel Stent for coronary Revasculations: The TiNOX Trial,' ACC Current J. Review, 14 [9] 43 (2005)
  10. M. Mosseri, I. Tamari, M. Plich, Y. Hasin, M. Brizines, A. Frimerman, H. Miller, J. Jafari, V. Guetta, M Solomon, and C. Lotan, 'Short and Long Term Outcome of the Titanium- NO stent Registry,' Cardiovascular Revascularization Medicine, 6 2-6 (2005) https://doi.org/10.1016/j.carrev.2005.04.004
  11. P. D. Maguire, J. A. McLaughlin, T. I. T. Okpalugo, P. Lemoine, P. Papakonstantinou, E. T. McAdams, M. Needham, A.A. Ogwu, M. Ball, and G. A. Abbas, 'Mechanical Stability, Corrosion Performance and Bioresponse of Amorphous Diamond-Like Carbon for Medical Stents and Guidewires,' Diamond Related Materials, 14 1277-88 (2005) https://doi.org/10.1016/j.diamond.2004.12.023
  12. N. Huang, Y. X. Leng, P. Yang, J. Y.Chen, H. Sun, J. Wang, G. J. Wan, A. S. Zhao, and P. D. Ding, 'Surface Modification of Coronary Artery Stent by Ti-O/Ti-N Complex Film Coating Prepared with Plasma Immersion Ion Implantation and Deposition,' Nuclear Inst. Methods in Phy. Research B., 242 18-21 (2006) https://doi.org/10.1016/j.nimb.2005.08.080
  13. C. L. Liu, P. K. Chu, G. Q. Lin, and M. Qi, 'Anti-corrosion Chacteristics of Nitride-coated AISI 316L Stainless steel Coronary Stent,' Surface & coating Technology, 201 2802- 06 (2006) https://doi.org/10.1016/j.surfcoat.2006.05.028
  14. F. Migliavacca, L. Petrini, M. Colombo, F. Auricchio, and R. Pietravissa, 'Mechanical Behavior of Coronary Stents Investigated through the Finite Element Method,' J. Biomechanics, 35 803-811 (2002) https://doi.org/10.1016/S0021-9290(02)00033-7
  15. N. David Chua, B. J. MacDonald, and M. S. J. Hashmi, 'Finite Element Simulation of Stent Expansion,' J. of Materials Processing Technology, 120 335-40 (2002) https://doi.org/10.1016/S0924-0136(01)01127-X
  16. S. N. D. Chua, B. J. MacDonald, M. S. J. Hashmi, Effects of Varying Slotted Stent Geometry on its Expansion Behaviour using Finite Element Method, J. of Mat. Processing Technology, 156 1764-71 (2004) https://doi.org/10.1016/j.jmatprotec.2004.04.395
  17. KIM, J. R. Rasmussen, 2001, 'Full-range Stress-Strain Curves for Stainless Steel Alloys,' J. Constuctional Steel Research, 59, 1 47-61 (2003) https://doi.org/10.1016/S0143-974X(02)00018-4
  18. ABAQUS user's manual, HKS, U.S.A. (2006)
  19. H. M. Burt and W. L. Hunter, 'Drug-eluting Stents: A Multidisciplinary Success Story,' Adv. Drug Delivery Review, 58 350-7 (2006) https://doi.org/10.1016/j.addr.2006.01.014