Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
권호 표지
DOI QR코드

DOI QR Code

Disseminated Intravascular Coagulation in a Patient Undergoing Removal of Metastatic Brain Tumor

  • Eom, Ki-Seong (Department of Neurosurgery, Wonkwang University College of Medicine) ;
  • Kim, Jong-Moon (Department of Neurosurgery, Wonkwang University College of Medicine) ;
  • Kim, Tae-Young (Department of Neurosurgery, Wonkwang University College of Medicine)
  • Published : 2008.11.28
Download PDF
⟨ Previous Next ⟩

Abstract

The authors present a case of 68-year-old woman who underwent resection of a metastatic adenocarcinoma in the left parietooccipital area. The intraoperative course was uneventful; however, after closure of the scalp incision, increased bleeding from the suture line was noted. A computerized tomography scan that was performed immediately after operation revealed acute epidural hemorrhage with mass effect under the bone flap. The patient developed disseminated intravascular coagulation and immediate re-exploration was performed. This patient was successfully treated owing to early recognition of the condition and immediate treatment with transfusion. Neurosurgeons should be alert that hypercoagulabe state is common in cancer patients and consumptive coagulopathy can occur after resection of metastatic brain tumor.

Keywords

References

  1. Berger MM, Ravussin P, Vielle G, Fankhauser H : Life-threatening hemorrhagic diathesis due to disseminated intravascular coagulation during elective brain tumor surgery. J Neurosurg Anesthesiol 7 : 26- 29, 1995 https://doi.org/10.1097/00008506-199501000-00005
  2. Brecknell JE, McLean CA, Hirano H, Malham GM : Disseminated intravascular coagulation complicating resection of a malignant meningioma. Br J Neurosurg 20 : 239-241, 2006 https://doi.org/10.1080/02688690600852647
  3. Ferasatkish R, Naddafnia H, Alavi SM, Naseri MH : Diagnosis and treatment of disseminated intravascular coagulation : a case report. Arch Iran Med 10 : 404-408, 2007
  4. Hartmann M, Sucker C, Messing M : Recombinant activated factor VII in the treatment of near-fatal bleeding during pediatric brain tumor surgery. Report of two cases and review of the literature. J Neurosurg 104 : 55-58, 2006
  5. Heesen M, Winking M, Kemkes-Matthes B, Deinsberger W, Dietrich GV, Matthes KJ, et al : What the neurosurgeon needs to know about the coagulation system. Surg Neurol 47 : 32-34, 1997 https://doi.org/10.1016/S0090-3019(96)00373-4
  6. Huang PS, Koo KE : Diffuse intravascular coagulation associated with brain tumor surgery in children. Pediatr Neurosurg 16 : 43- 47, discussion 47, 1990 https://doi.org/10.1159/000120504
  7. Levi M, Ten Cate H : Disseminated intravascular coagulation. N Engl J Med 341 : 586-592, 1999 https://doi.org/10.1056/NEJM199908193410807
  8. Matjasko MJ, Ducker TB : Disseminated intravascular coagulation associated with removal of a primary brain tumor. J Neurosurg 47 : 476-480, 1977
  9. Portugal JR, Alencar A, Brito Lira LC, Carvalho P : Melanotic meningioma complicated by disseminated intravascular coagulation. Surg Neurol 21 : 275-281, 1984 https://doi.org/10.1016/0090-3019(84)90202-7
  10. Sallah S, Wan JY, Nguyen NP, Hanrahan LR, Sigounas G : Disseminated intravascular coagulation in solid tumors : clinical and pathologic study. Thromb Haemost 86 : 828-833, 2001 https://doi.org/10.1055/s-0037-1616139
  11. Selman WR, Miller CA : Hematology and coagulation : Physiology, pathophysiology, and management, in Wirth FP, Hutcheson RA (eds) : Neurosurgical critical care. Baltimore : Williams & Wilkins, 1987, pp133-154
  12. Thoron L, Arbit E : Hemostatic changes in patients with brain tumors. J Neurooncol 22 : 87-100, 1994 344 https://doi.org/10.1007/BF01052885

Cited by

  1. Disseminated Intravascular Coagulation During Resection of a Meningioma: Case Report vol.68, pp.4, 2011, https://doi.org/10.1227/neu.0b013e31820a181a