Acute Hepatic Failure Induced by Xylitol Toxicosis in Two Dogs

  • Lim, Chae-Young (Departments of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Yoo, Jong-Hyun (BK21 program of Integrative network systems for veterinarians in basic science, industrial animals and preventive medicines, Konkuk University) ;
  • Kim, Chun-Geun (Departments of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Park, Chul (Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California) ;
  • Park, Hee-Myung (Departments of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • Published : 2008.12.31

Abstract

Two dogs were referred due to vomiting, depression and anorexia after ingestion of xylitol gum. Both dogs were presented with hepatic failure and one dog had concurrent renal failure. Aggressive supportive treatment was performed, but these dogs died. Necropsy of one dog revealed acute hepatic necrosis, severe renal damages, and hemoperitoneum. This case report demonstrates potential hazard of xylitol toxicity for dogs with clinicopathological and pathological findings.

Keywords

References

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