Effects of five element constitutional acupuncture(Sa-am acupuncture) using needle manipulation to sedate Six Fu-Organ on serum lipid and liver function of hyperlipidemic rats induced by high fat diet

사암침법(舍岩鍼法) 중 육양경(六陽經)의 승격(勝格) 혈위(穴位)에 대한 염전보사(捻轉補瀉) 침자(鍼刺)가 고지방식이(高脂肪食餌)로 유발된 고지혈증(高脂血症) 백서(白鼠)에 미치는 영향(影響)

  • Youn, Dae-Hwan (Dept. of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Na, Chang-Su (Dept. of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Choi, Tae-Jin (Dept. of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Yun, Jeong-Young (Dept. of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Ryu, Yeon-Hee (Dept. of Medical Research Korea Institute of Oriental Medicine) ;
  • Choi, Chan-Hun (Dept. of Physiology, College of Oriental Medicine, Dongshin University) ;
  • Choi, Sun-Mi (Dept. of Medical Research Korea Institute of Oriental Medicine)
  • 윤대환 (동신대학교 한의학과 경락경혈학교실) ;
  • 나창수 (동신대학교 한의학과 경락경혈학교실) ;
  • 최태진 (동신대학교 한의학과 경락경혈학교실) ;
  • 윤정영 (동신대학교 한의학과 경락경혈학교실) ;
  • 류연희 (한국한의학연구원 의료연구부) ;
  • 최찬헌 (동신대학교 한의학과 생리학교실) ;
  • 최선미 (한국한의학연구원 의료연구부)
  • Published : 2008.12.27

Abstract

Objective : The aim of this research was to investigate the effect on five element constitutional acupuncture(Sa-am acupuncture) at 4 acupoints by needle manipulation to sedate Six Fu-Organ on hyperlipidemia induced by high fat diet in rats. Method : We recorded data of weight gain, food intake, food efficiency, weight of liver, heart, spleen, lung, kidney, levels of total cholesterol, triglyceride, HDL-cholesterol, AST, ALT in serum of rats fed high fat diet for 5 weeks. Spraque Dawley rats were divided into eight groups(normal; normal diet and non-acupuncture group, control; non-acupuncture group, Acu-LI; acupuncture at $SI_5{\cdot}LI_5{\cdot}BL_{66}{\cdot}LI_2$ group, Acu-ST; acupuncture at $GB_{41}{\cdot}ST_{43}{\cdot}LI_1{\cdot}ST_{45}$, Acu-SI; acupuncture at $BL_{66}{\cdot}SI_2{\cdot}ST_{36}{\cdot}SI_8$, Acu-BL; acupuncture therapy at $ST_{36}{\cdot}BL_{40}{\cdot}GB_{41}{\cdot}BL_{65}$, Acu-TE; acupuncture at $BL_{66}{\cdot}TE_2{\cdot}ST_{36}{\cdot}TE_{10}$, Acu-GB; acupuncture at $LI_1{\cdot}GB_{44}{\cdot}SI_5{\cdot}GB_{38}$. After needles inserted, it was rotated clockwise and anticlockwise 12 times on rats fed high fat diet. Results : The body weight was decreased in Acu-SI, Acu-TE, Acu-GB group, /the food intake was decreased in Acu-TE, / the food efficiency was decreased in Acu-SI, /serum triglyceride was decreased in Acu-LI, Acu-ST, Acu-BL, Acu-GB, /serum total cholesterol was decreased in Acu-LI, Acu-BL, serum ALP was decreased in Acu-LI, Acu-ST, Acu-BL, Acu-TE, Acu-GB. While the relative weight of heart was increased in Acu-LI, Acu-SI, the relative weight of kidney was increased in Acu-SI, Acu-GB. Conclusion : These results suggest that five element constitutional acupuncture(Sa-am acupuncture) may be having an therapeutic influence on hyperlipidemia induced by high fat diet. Further researches of acupuncture manipulation are needed in the future based on our study.

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