Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
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Anti-aging and Anti-Oxidant Effect of Bopyewon-tang in liver and Lung Cell of SD Rats

보폐원탕(補肺元湯)이 노화쥐의 간장과 폐장 세포의 항노화 및 항산화능에 미치는 영향

  • Bae, Jung-Kyu (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Daejeon University) ;
  • Ahn, Taek-Won (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Daejeon University)
  • 배정규 (대전한의대학교 한의과대학 사상체질과) ;
  • 안택원 (대전한의대학교 한의과대학 사상체질과)
  • Published : 2008.12.30
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Abstract

1. Objective The purpose of this study is to investigate the anti-aging and anti-oxidant effects of Bopyewon-tang(BPW) in Liver and Lung cell. 2. Methods This experiment was used the tissue of liver and lung cells of 6, 52 and 68 weeks old SD rats. Each age group was again divided into three groups. One group, as normal group, was not-treated cells, another group, as control group, was saline-treated cells, and the last group, as experimental group, was BPW -treated cells. After culture for 48 hours, each groups measured the level of SOD, GSH, MDA and NO in the tissue of liver and lung cells. 3. Results and Conclusion 1. The activity of SOD in liver of in 52 w-BPW group, 68 w-BPW group, and in lung of 68 w-BPW were significantly increased in comparison with those of the normal groups. 2. The levels of NO in liver of in 68 w-BPW group was significantly decreased in comparison with those of the normal groups. 3. The levels of MDA in lung of in 68 w-BPW group was significantly decreased in comparison with those of the normal groups.

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